小剂量阿糖胞苷治疗急性非淋巴细胞白血病
Low dose cytosine arabinoside in the treatment of acute non-lymphocytic leukaemia.
作者信息
Jensen M K, Ahlbom G
出版信息
Scand J Haematol. 1985 Mar;34(3):261-3. doi: 10.1111/j.1600-0609.1985.tb02789.x.
Abstract
Complete remissions were obtained with low dose cytosine arabinoside (ARA-C) in 8 of 21 previously untreated patients with ANLL above 60 years of age and in 2 of 4 previously treated patients below 60 years of age. 7 of the patients remain in remission after 1-26 months. The results demonstrate that low dose ARA-C with rather low toxicity may induce remissions in elderly patients with ANLL.
摘要
21例60岁以上未经治疗的急性非淋巴细胞白血病（ANLL）患者中，8例使用小剂量阿糖胞苷（ARA-C）获得完全缓解；4例60岁以下经治患者中，2例获得完全缓解。7例患者在1 - 26个月后仍处于缓解状态。结果表明，毒性较低的小剂量ARA-C可诱导老年ANLL患者缓解。
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