Kodithuwakku Piyumi, Weerakoon Harshi, Silva Anjana, Wickramasinghe Susiji, Weerakoon Kosala
Department of Parasitology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka.
Department of Biochemistry, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, Sri Lanka.
BMJ Open. 2025 Feb 8;15(2):e092600. doi: 10.1136/bmjopen-2024-092600.
Human ocular trematode infections, caused by parasitic flatworms, are a significant public health concern worldwide. It can lead to mild-to-severe consequences if untreated. This protocol outlines a scoping review methodology, which aims to explore the knowledge on the aetiopathogenesis, clinico-epidemiological and diagnostic aspects, and patient perspectives related to ocular trematode infections in humans.
The review, including the development of the review protocol, will be conducted over 2 years from January 2024. The Joanna Briggs Institute Reviewers' Manual and the framework developed by Arksey and O'Malley will be used as the guidelines for the scoping review that is suggested in this protocol. Accordingly, the PCC (Population, Concept, Context) framework and three-stage search strategy will be used to develop the research question and to conduct the search respectively. Publications up to December 2024 will be searched across multiple databases, including MEDLINE/PubMed, Scopus, Science Direct, CINAHL and Google Scholar.
Since the study will make use of secondary data, ethical approval will not be required. The scoping review's findings will be published in a scientific journal and presented at relevant conferences, aiming to improve the disease outcomes through guiding future research in ocular trematode infections and informing potential strategies to uplift the disease control and prevention measures and patient care.
由寄生扁虫引起的人类眼部吸虫感染是全球重大的公共卫生问题。如果不治疗,可能会导致从轻到重的后果。本方案概述了一种范围综述方法,旨在探索关于人类眼部吸虫感染的病因发病机制、临床流行病学和诊断方面以及患者观点的知识。
该综述,包括综述方案的制定,将从2024年1月开始,历时2年进行。乔安娜·布里格斯研究所审稿人手册以及阿克西和奥马利制定的框架将用作本方案中建议的范围综述的指南。因此,将使用PCC(人群、概念、背景)框架和三阶段搜索策略分别制定研究问题和进行搜索。将在多个数据库中搜索截至2024年12月的出版物,包括MEDLINE/ PubMed、Scopus、Science Direct、CINAHL和谷歌学术。
由于该研究将使用二手数据,因此无需伦理批准。范围综述的结果将发表在科学期刊上,并在相关会议上展示,旨在通过指导未来关于眼部吸虫感染的研究以及为提升疾病控制和预防措施及患者护理的潜在策略提供信息,来改善疾病结局。