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中暑合并脓毒症:一例病例报告及文献综述

Heat stroke with sepsis: A case report and review of the literature.

作者信息

Wei Suyu, Sun Liang

机构信息

Department of Emergency, Shandong Provincial Third Hospital, Shandong University, Jinan, Shandong, China.

出版信息

J Int Med Res. 2025 Feb;53(2):3000605251315353. doi: 10.1177/03000605251315353.

DOI:10.1177/03000605251315353
PMID:39922802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11807274/
Abstract

Heat stroke, triggered by excessive heat exposure or intense physical activity, is a medical condition characterized by a rapid rise in core body temperature, central nervous system dysfunction and multiorgan failure. A patient presented with heat stroke and was unconscious. During treatment, we identified a range of complications, including shifted flora, coagulation abnormalities, liver damage and renal failure-indicating multiorgan dysfunction. We administered antibiotic therapy, blood purification and other comprehensive treatments, leading to the patient's recovery and subsequent discharge. For cases of heat stroke in an intensive care setting, clinicians must recognize the condition early and act swiftly to reduce body temperature. Additionally, the early use of antibiotics can help prevent microbial imbalance. For eligible patients, hemodialysis should be initiated promptly to manage renal complications effectively.

摘要

中暑是由过度暴露于高温环境或剧烈体育活动引发的一种病症,其特征为核心体温迅速升高、中枢神经系统功能障碍和多器官衰竭。一名中暑患者被送来时已失去意识。在治疗过程中,我们识别出一系列并发症,包括菌群移位、凝血异常、肝损伤和肾衰竭,这表明出现了多器官功能障碍。我们给予了抗生素治疗、血液净化及其他综合治疗,最终患者康复并出院。对于重症监护环境下的中暑病例,临床医生必须尽早识别病情并迅速采取行动降低体温。此外,早期使用抗生素有助于预防微生物失衡。对于符合条件的患者,应及时启动血液透析以有效处理肾脏并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db21/11807274/dbb9b3facebb/10.1177_03000605251315353-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db21/11807274/dbb9b3facebb/10.1177_03000605251315353-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db21/11807274/dbb9b3facebb/10.1177_03000605251315353-fig1.jpg

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本文引用的文献

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[Observation on the efficacy of continuous veno-venous hemodia-filtration combined with hemoperfusion HA380 in the treatment of 15 cases of heat stroke with multiple organ dysfunction syndrome].[连续性静脉-静脉血液透析滤过联合HA380血液灌流治疗15例中暑合并多器官功能障碍综合征的疗效观察]
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Vancomycin modestly attenuates symptom severity during onset of and recovery from exertional heat stroke in mice.
万古霉素在小鼠运动性热射病发作和恢复期间适度减轻症状严重程度。
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ACSL4 contributes to ferroptosis-mediated rhabdomyolysis in exertional heat stroke.ACSL4 促进运动性中暑中 ferroptosis 介导的横纹肌溶解。
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