Miniati Mario, Battani Alessandra, Palagini Laura, Ciacchini Rebecca, Conversano Ciro, Orrù Graziella, Perugi Giulio, Marazziti Donatella, Gemignani Angelo
Psychiatric Clinic, Department of Clinical and Experimental Medicine, University of Pisa, 56126Pisa, Italy.
Department of Surgical, Medical and Molecular Pathology and of Critical Care Medicine, University of Pisa, 56126Pisa, Italy.
CNS Spectr. 2025 Feb 10;30(1):e36. doi: 10.1017/S1092852925000100.
To investigate dispositional mindfulness (DM), interoceptive awareness (AI), and the occurrence of panic-agoraphobic spectrum signs and symptoms in a non-clinical population.
The study involved a general population sample ( = 141), aged between 18 and 40, evaluated with the Panic-Agoraphobic Spectrum Self-Report Lifetime Version (PAS-SR-LT), the Mindful Attention Awareness Scale (MAAS), and the Multidimensional Assessment of Interoceptive Awareness (MAIA). Instruments were administered with an online procedure (Microsoft Forms). The Bioethics Committee of the University of Pisa approved the study (protocol #0105635/2023).
Panic-agoraphobic spectrum was detected in more than 50% of our sample (PAS-SR Total Score ≥ 35). According to the MAIA assessment, subjects who scored above the PAS-SR threshold were more afraid and less able to distract attention from their bodily sensations. A binary logistic regression analysis was performed to evaluate if MAIA and MAAS dimensions were able to predict the presence of a more severe panic-spectrum symptomatology. The PAS-SR cut-off score <35 versus ≥35 was adopted as the dependent variable. "Age" and "gender" (categorical), MAAS, and MAIA scores were inserted as covariates. MAAS "Total Score" (OR = .955; CI = .924-.988; = .007), and MAIA "Not worrying" (OR = .826; CI = .707-.964; = .016) predicted for a less relevant panic-agoraphobic spectrum phenomenology, resulting as "protective" factors.
Progression from interoceptive processing to mindful abilities to resilience against panic catastrophizing of bodily sensation is far from being clarified. However, our study provides information on a panic-agoraphobic spectrum phenotype characterized by low levels of mindful attitudes and less interoceptive abilities.
在非临床人群中研究特质正念(DM)、内感受性觉知(AI)以及惊恐 - 场所恐惧谱系体征和症状的发生情况。
该研究纳入了141名年龄在18至40岁之间的普通人群样本,使用惊恐 - 场所恐惧谱系自我报告终生版(PAS - SR - LT)、正念注意觉知量表(MAAS)和内感受性觉知多维评估(MAIA)进行评估。通过在线程序(Microsoft Forms)发放问卷。比萨大学伦理委员会批准了该研究(协议编号#0105635/2023)。
在我们超过50%的样本中检测到惊恐 - 场所恐惧谱系(PAS - SR总分≥35)。根据MAIA评估,PAS - SR阈值以上得分的受试者更害怕,且更难以将注意力从身体感觉上转移。进行二元逻辑回归分析以评估MAIA和MAAS维度是否能够预测更严重惊恐谱系症状的存在。采用PAS - SR截止分数<35与≥35作为因变量。将“年龄”和“性别”(分类变量)、MAAS和MAIA得分作为协变量纳入。MAAS“总分”(OR = 0.955;CI = 0.924 - 0.988;P = 0.007)以及MAIA“不担忧”(OR = 0.826;CI = 0.707 - 0.964;P = 0.016)预测了不太相关的惊恐 - 场所恐惧谱系现象学,结果为“保护”因素。
从内感受性处理到正念能力再到抵御身体感觉惊恐灾难化的复原力的进展远未明确。然而,我们的研究提供了关于一种以低水平正念态度和较低内感受性能力为特征的惊恐 - 场所恐惧谱系表型的信息。