Severino Maria Inês, Freitas Cátia, Pimenta Vanessa, Nouar Farid, Pinto Moisés L, Serre Christian
CERENA, Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.
Institut des Matériaux Poreux de Paris, ESPCI Paris, Ecole Normale Supérieure, CNRS, PSL University, 75005 Paris, France.
Ind Eng Chem Res. 2025 Jan 22;64(5):2708-2718. doi: 10.1021/acs.iecr.4c02618. eCollection 2025 Feb 5.
Understanding the impact of MOF synthesis conditions on the production cost is vital in order to have a competitive product with a view toward industrial applications. Here, considering the benchmark mesoporous iron(III) trimesate MIL-100(Fe) as a prototypical example, we show that the production cost can reach <30 $/kg if a careful selection of the synthetic route is made. Two routes were considered in the analysis, using sulfate and nitrate as iron sources. A new optimized synthesis protocol in a 5 L laboratory pilot-scale reactor based on iron sulfate was developed using optimized sustainable aqueous ambient pressure conditions, leading to larger particles and a higher space-time yield. Based on reliable pilot-scale data and established chemical engineering estimation methods, this leads to a significantly lower production cost of high-quality MIL-100(Fe), achieving a potential competitive product.
为了生产出具有工业应用竞争力的产品，了解金属有机框架（MOF）合成条件对生产成本的影响至关重要。在此，以基准介孔均苯三甲酸铁（III）MIL-100（Fe）作为典型示例，我们表明，如果仔细选择合成路线，生产成本可降至<30美元/千克。分析中考虑了两条路线，分别使用硫酸盐和硝酸盐作为铁源。基于优化的可持续常压水相条件，在5升实验室中试规模反应器中开发了一种基于硫酸铁的新优化合成方案，可得到更大颗粒和更高的时空产率。基于可靠的中试规模数据和既定的化学工程估算方法，这使得高质量MIL-100（Fe）的生产成本显著降低，从而获得一种具有潜在竞争力的产品。
