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2020年和2021年巴西北部巨细胞瘤患者的治疗情况

TREATMENT OF PATIENTS WITH GIANT CELL BONE TUMOR IN NORTHERN BRAZIL, IN 2020 AND 2021.

作者信息

do Couto Fernando Brasil, Yonamine Eduardo Sadao, Magno Felipe Guimarães, Favacho-Silva Ana Beatriz, de Brito Carlos Rafael Alves, Brito Thiago Raphael Brasil

机构信息

Hospital Ophir Loyola, Orthopaedic Oncology Department, Belém, PA, Brazil.

Santa Casa de Misericórdia de São Paulo, Orthopaedic Oncology Department, São Paulo, SP, Brazil.

出版信息

Acta Ortop Bras. 2025 Feb 3;33(1):e285342. doi: 10.1590/1413-785220253301e285342. eCollection 2025.

DOI:10.1590/1413-785220253301e285342
PMID:39927320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11801210/
Abstract

OBJECTIVE

This study aimed to evaluate the profile of patients diagnosed with giant cell tumors treated at the Ophir Loyola Hospital.

METHOD

An analytical study in the form of a retrospective cohort, conducted through a review of patient medical records and imaging exams of individuals treated at the hospital between January 1, 2020, and December 31, 2021.

RESULT

A total of 19 patients were evaluated, with an average time of 10.5 months between diagnostic suspicion and the first consultation with the Orthopedic Oncology team.

CONCLUSION

Among the patients studied, 73% were presented with advanced-stage disease, requiring aggressive surgical treatment with wide resection and replacement with an endoprosthesis.

摘要

目的

本研究旨在评估在奥菲尔·洛约拉医院接受治疗的巨细胞瘤患者的概况。

方法

采用回顾性队列分析研究，通过查阅2020年1月1日至2021年12月31日期间在该医院接受治疗的患者的病历和影像学检查进行。

结果

共评估了19例患者，从诊断怀疑到首次咨询骨肿瘤学团队的平均时间为10.5个月。

结论

在所研究的患者中，73%患有晚期疾病，需要进行广泛切除并使用假体置换的积极手术治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b7/11801210/393325f6af3b/1413-7852-aob-33-01-e285342-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b7/11801210/15d9c7254a32/1413-7852-aob-33-01-e285342-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b7/11801210/393325f6af3b/1413-7852-aob-33-01-e285342-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b7/11801210/15d9c7254a32/1413-7852-aob-33-01-e285342-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76b7/11801210/393325f6af3b/1413-7852-aob-33-01-e285342-gf02.jpg

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本文引用的文献

1
GIANT CELL TUMOR OF BONE: A MULTICENTER EPIDEMIOLOGICAL STUDY IN BRAZIL.骨巨细胞瘤：巴西的一项多中心流行病学研究。
Acta Ortop Bras. 2024 Mar 22;32(1):e273066. doi: 10.1590/1413-785220243201e273066. eCollection 2024.
2
Argon Beam Coagulation as an Adjuvant for Extended Curettage for Giant Cell Tumors of the Bone: A Study of 50 Cases.氩离子束凝固术作为骨巨细胞瘤扩大刮除术的辅助治疗：50例研究
Rev Bras Ortop (Sao Paulo). 2022 Feb 15;58(2):211-221. doi: 10.1055/s-0042-1742600. eCollection 2023 Apr.
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[Low-cost reconstructive treatment after resection of distal radius giant cell tumor].
[桡骨远端骨巨细胞瘤切除术后的低成本重建治疗]
Acta Ortop Mex. 2022 May-Jun;36(3):190-194.
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Treatment of Patients Diagnosed with Giant Cell Tumor of Bone: Experience of a Philanthropic Hospital in the State of Piauí, Brazil.骨巨细胞瘤确诊患者的治疗：巴西皮奥伊州一家慈善医院的经验
Rev Bras Ortop (Sao Paulo). 2022 Jul 7;57(5):802-806. doi: 10.1055/s-0042-1744498. eCollection 2022 Oct.
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Giant Cell Tumor of Bone: Effect of Longer Dosing Intervals of Denosumab on Tumor Control and Bone-related Complications.骨巨细胞瘤：地舒单抗更长给药间隔对肿瘤控制和骨相关并发症的影响。
Oncologist. 2022 Jul 5;27(7):595-599. doi: 10.1093/oncolo/oyac066.
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[Denosumab as a treatment for giant cell tumor of bone. Indications, results and side effects].[地诺单抗治疗骨巨细胞瘤。适应证、疗效及副作用]
Medicina (B Aires). 2021;81(5):767-773.
7
Giant Cell Tumor of Bone: An Update.骨巨细胞瘤：最新进展。
Curr Oncol Rep. 2021 Mar 22;23(5):51. doi: 10.1007/s11912-021-01047-5.
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Giant Cell Tumor of the Ring Finger Distal Phalanx.环指末节骨干巨细胞瘤。
J Hand Surg Am. 2021 Mar;46(3):249.e1-249.e5. doi: 10.1016/j.jhsa.2020.04.005. Epub 2020 Jun 8.
9
Outcomes of En bloc resection followed by reconstruction of giant cell tumor around knee and distal radius. A case series.膝关节及桡骨远端骨巨细胞瘤整块切除并重建后的结果。病例系列报道
Ann Med Surg (Lond). 2019 Dec 6;49:61-66. doi: 10.1016/j.amsu.2019.11.019. eCollection 2020 Jan.
10
Inoperable Sacral Giant Cell Tumor: Therapeutic Options and Pain Control.不可切除的骶骨巨细胞瘤：治疗选择与疼痛控制
Rev Bras Ortop (Sao Paulo). 2019 May;54(3):347-352. doi: 10.1055/s-0039-1692450. Epub 2019 Jun 27.