脐带血间充质干细胞在膝关节软骨修复中的临床研究进展：综述
Clinical research progress of umbilical cord blood mesenchymal stem cells in Knee articular cartilage repair: A review.
作者信息
Liao ZhongKai
机构信息
The Second Affiliated Hospital of Hainan Medical College, Master of Medicine, Haikou, China.
出版信息
Medicine (Baltimore). 2025 Feb 7;104(6):e41402. doi: 10.1097/MD.0000000000041402.
Abstract
Umbilical cord blood mesenchymal stem cells (UCB-MSCs) are a type of adult stem cell with multipotent differentiation potential and immunoregulatory functions, primarily found in neonatal cord blood. Due to their noninvasive collection method, abundance, and ease of preservation, UCB-MSCs represent a promising biological material. This review examines the clinical research on UCB-MSCs in knee articular cartilage repair, highlighting their regenerative potential for treating knee joint cartilage defects. Our aim is to provide insights into current applications and propose directions for future research, focusing on optimizing clinical use and enhancing patient outcomes.
摘要
脐带血间充质干细胞（UCB - MSCs）是一种具有多能分化潜能和免疫调节功能的成体干细胞，主要存在于新生儿脐带血中。由于其采集方法无创、来源丰富且易于保存，UCB - MSCs是一种很有前景的生物材料。本综述探讨了UCB - MSCs在膝关节软骨修复方面的临床研究，突出了它们在治疗膝关节软骨缺损方面的再生潜力。我们的目的是深入了解当前的应用情况，并为未来的研究提出方向，重点是优化临床应用并提高患者治疗效果。
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