Fuse H, Masukagami T, Kataumi Z, Shimazaki J
Hinyokika Kiyo. 1985 Jan;31(1):81-5.
From August, 1981 to May, 1984, we measured gamma-seminoprotein in the serum of 51 untreated patients with prostatic cancer in the Chiba University Hospital. Prostatic acid phosphatase (radioimmunoassay) in serum was also measured in these patients. We also measured gamma-seminoprotein and prostatic acid phosphatase in serum of patients under control by hormonal treatment and of reactivated patients. In untreated stage B and stage C cases, positive rate of gamma-seminoprotein in serum was larger than that of prostatic acid phosphatase. Therefore the measurement of gamma-seminoprotein in serum is considered to be useful in the diagnosis of early prostatic cancer. Four weeks after hormonal treatment, gamma-seminoprotein in the serum of 74% of the patients returned to the normal level. The positive rate of gamma-seminoprotein in the serum of reactivated patients is significantly larger than that of the patients under control by hormonal therapy.
1981年8月至1984年5月，我们在千叶大学医院对51例未经治疗的前列腺癌患者的血清γ-精蛋白进行了检测。同时还对这些患者血清中的前列腺酸性磷酸酶（放射免疫测定法）进行了检测。我们还检测了接受激素治疗的对照患者以及复发患者血清中的γ-精蛋白和前列腺酸性磷酸酶。在未经治疗的B期和C期病例中，血清γ-精蛋白的阳性率高于前列腺酸性磷酸酶。因此，血清γ-精蛋白检测被认为对早期前列腺癌的诊断有用。激素治疗四周后，74%患者血清中的γ-精蛋白恢复到正常水平。复发患者血清中γ-精蛋白的阳性率明显高于接受激素治疗的对照患者。
