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一名秘鲁女性患登革热后亚急性甲状腺炎:病例报告及文献综述

Post-dengue subacute thyroiditis in a Peruvian woman: case report and literature review.

作者信息

Trujillo-Aguirre María de Lourdes, Marcilla-Truyenque Rosa Laurie, Quiroz-Aldave Juan Eduardo, Morales-Moreno Adriana, Durand-Vásquez María Del Carmen, Concepción-Zavaleta Marcio José, Paz-Ibarra José

机构信息

División de Endocrinología, Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú.

Servicio de Medicina, Hospital de Apoyo Chepén. Chepén, Perú.

出版信息

Rev Peru Med Exp Salud Publica. 2025 Jan 31;41(4):431-437. doi: 10.17843/rpmesp.2024.414.14228.

Abstract

Expanded dengue syndrome are unusual conditions, such as subacute thyroiditis (SAT). We present the case of a 38-year-old woman who had dengue without alarm signs for a month, along with cervical pain and increased cervical volume, palpitations, tremor and dysphagia. Hormonal evaluation, ultrasound and thyroid scintigraphy were consistent with SAT. She received corticoids for two months, with remission after four months. SAT is characterized by neck pain, fever and symptoms of thyrotoxicosis. It is associated with viral infections and it comprises a phase of thyrotoxicosis followed by hypothyroidism. Diagnosis involves hormonal and biochemical tests, thyroid ultrasound with Doppler and scintigraphy. This condition is managed with non-steroidal anti-inflammatory drugs and corticosteroids, according to severity. SAT, an infrequent manifestation of dengue, requires a high degree of suspicion and appropriate management. A review of published cases of SAT due to dengue was carried out in the Scopus, PubMed and Web of Science databases, finding six reported cases, mostly in men.

摘要

登革热综合征扩展表现为一些不常见的病症,如亚急性甲状腺炎(SAT)。我们报告一例38岁女性病例,她患登革热一个月,无警示体征,伴有颈部疼痛、颈部肿大、心悸、震颤和吞咽困难。激素评估、超声检查和甲状腺闪烁扫描结果与亚急性甲状腺炎相符。她接受了两个月的皮质类固醇治疗,四个月后病情缓解。亚急性甲状腺炎的特征为颈部疼痛、发热和甲状腺毒症症状。它与病毒感染有关,包括一个甲状腺毒症期,随后是甲状腺功能减退期。诊断包括激素和生化检查、甲状腺多普勒超声检查和闪烁扫描。根据病情严重程度,这种病症采用非甾体抗炎药和皮质类固醇进行治疗。亚急性甲状腺炎作为登革热的一种罕见表现,需要高度怀疑并进行适当处理。我们在Scopus、PubMed和科学网数据库中对已发表的登革热所致亚急性甲状腺炎病例进行了回顾,发现6例报告病例,大多数为男性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58f4/11797575/eda682ca90c4/rpmesp-41-04-14228-g001.jpg

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