Zhu L, Wang Y H, Li S Y, Wen Y, Hao Y R, Wang J Y, Jie Y
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China.
Zhonghua Yan Ke Za Zhi. 2025 Feb 14;61(2):96-103. doi: 10.3760/cma.j.cn112142-20240714-00300.
To investigate the impact of eyeliner tattooing on the ocular surface, the morphology and function of meibomian glands, and to explore its potential influence on ocular surface health. A retrospective cohort study was conducted. A total of 31 female subjects (62 eyes) with eyeliner tattoos who visited the outpatient department of Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University from April to September 2022 due to visual fatigue and other reasons were included as the eyeliner group, and 28 age-matched female subjects (56 eyes) without eyeliner tattoos were included as the control group. Questionnaires, tear meniscus height measurement, evaluation of the distance between meibomian gland imaging and the eyeliner, detection of the thickness of the lipid layer of the tear film and blink parameters, tear secretion test and tear film break-up time(BUT) measurement, meibomian gland function score and other examinations were carried out for all subjects. The main indicators included the Ocular Surface Disease Index (OSDI) score, tear meniscus height (TMH), lipid layer thickness of the tear film, tear secretion test, and BUT, etc. The OSDI score of the eyeliner group was (43.05±19.00) points, which was significantly higher than that of the control group [(20.70±12.42) points] (<0.05). The TMH of the eyeliner group was (0.19±0.06) mm, and the BUT was (4.19±1.28) s, both of which were lower than those of the control group [(0.31±0.16) mm and (5.64±2.16) s], and the differences were statistically significant (both 0.05). The scores of meibomian gland loss degree, meibomian gland secretion, and meibomian gland excretion ability in the eyeliner group were all significantly higher than those in the control group (all <0.05). In addition, the proportion of incomplete blinks in the eyeliner group was significantly higher than that in the control group (<0.05). The distance between the eyeliner and the opening of the meibomian gland was positively correlated with the scores of meibomian gland loss degree and meibomian gland excretion ability (=0.432, 0.539; both <0.05). Eyeliner tattooing has a significant impact on the ocular surface and the morphology and function of meibomian glands, resulting in an increase in the OSDI score, a decrease in the TMH and BUT, a decline in meibomian gland function, and an increase in the proportion of incomplete blinks, which may increase the risks of ocular discomfort and dry eye.
为探究纹眼线对眼表、睑板腺形态及功能的影响，并探讨其对眼表健康的潜在影响。进行了一项回顾性队列研究。选取2022年4月至9月因视疲劳等原因就诊于首都医科大学附属北京同仁医院北京同仁眼科中心门诊的31例纹眼线女性受试者（62只眼）作为纹眼线组，选取28例年龄匹配的未纹眼线女性受试者（56只眼）作为对照组。对所有受试者进行问卷调查、泪河高度测量、睑板腺成像与眼线距离评估、泪膜脂质层厚度及眨眼参数检测、泪液分泌试验及泪膜破裂时间（BUT）测量、睑板腺功能评分等检查。主要指标包括眼表疾病指数（OSDI）评分、泪河高度（TMH）、泪膜脂质层厚度、泪液分泌试验及BUT等。纹眼线组OSDI评分为（43.05±19.00）分，显著高于对照组[（20.70±12.42）分]（<0.05）。纹眼线组TMH为（0.19±0.06）mm，BUT为（4.19±1.28）s，均低于对照组[（0.31±0.16）mm和（5.64±2.16）s]，差异有统计学意义（均<0.05）。纹眼线组睑板腺缺失程度、睑板腺分泌及睑板腺排泄能力评分均显著高于对照组（均<0.05）。此外，纹眼线组不完全眨眼比例显著高于对照组（<0.05）。眼线与睑板腺开口的距离与睑板腺缺失程度及睑板腺排泄能力评分呈正相关（r=0.432、0.539；均<0.05）。纹眼线对眼表及睑板腺形态和功能有显著影响，导致OSDI评分升高、TMH和BUT降低、睑板腺功能下降及不完全眨眼比例增加，可能增加眼部不适和干眼的风险。
