Lesourd B M, Corriel R N, McBryde J L, Kniker W T
Ann Allergy. 1985 May;54(5):446-52.
The Multitest CMI system was used to measure cutaneous delayed type hypersensitivity (DTH) to a standardized battery of seven recall antigens in 448 healthy school children in relation to sex, age, race, and socioeconomic groups. Blacks demonstrated highest overall DTH, hispanics were intermediate, and whites were lowest. There was a trend for males to be more reactive than females at certain ages in each race. Incidence of reduced DTH scores (relative to adult values) was somewhat increased in the youngest school children, chiefly whites. Incidence and size of DTH responses to certain antigens were consistently higher in the blacks and/or hispanics as compared with whites. Blacks lived almost exclusively in the "poorer" school district, hispanics were evenly divided in both districts, while whites were mostly from the "affluent" district. Level of DTH appeared to be greatest in children from relatively poor homes possibly reflecting more intense and frequent exposure to ubiquitous microorganisms.
使用Multitest CMI系统对448名健康学童针对一组由七种标准化回忆抗原组成的抗原库进行皮肤迟发型超敏反应（DTH）检测，检测与性别、年龄、种族和社会经济群体相关。黑人总体DTH最高，西班牙裔居中，白人最低。在每个种族的特定年龄段，男性比女性更具反应性。最年幼的学童（主要是白人）中，DTH评分降低（相对于成人值）的发生率有所增加。与白人相比，黑人和/或西班牙裔对某些抗原的DTH反应发生率和反应大小一直更高。黑人几乎都住在“较贫困”的学区，西班牙裔在两个学区分布均匀，而白人大多来自“富裕”学区。来自相对贫困家庭的儿童DTH水平似乎最高，这可能反映了他们更频繁且强烈地接触无处不在的微生物。
