间质性肺疾病潜在的特发性炎性肌病的识别
Recognition of Idiopathic Inflammatory Myopathies Underlying Interstitial Lung Diseases.
作者信息
Morina Giulia, Sambataro Domenico, Libra Alessandro, Palmucci Stefano, Colaci Michele, La Rocca Gaetano, Ferro Francesco, Carli Linda, Baldini Chiara, Liuzzo Santa Valentina, Vancheri Carlo, Sambataro Gianluca
机构信息
Department of Clinical and Experimental Medicine, Regional Referral Center for Rare Lung Diseases, Policlinico "G.Rodolico-San Marco", University of Catania, 95123 Catania, Italy.
Artroreuma S.R.L., Outpatient Clinic Associated with the Regional Health System, Mascalucia, 95030 Catania, Italy.
出版信息
Diagnostics (Basel). 2025 Jan 24;15(3):275. doi: 10.3390/diagnostics15030275.
Interstitial Lung Disease (ILD) is one of the most common causes of mortality in idiopathic Inflammatory Myopathies (IIM). Despite these conditions being commonly associated with proximal weakness, skin rashes and arthritis, ILD can be the first or the sole clinical feature in up to 60% of patients, potentially leading to incorrect diagnosis. The early recognition of an underlying IIM in ILD patients can allow for prompt treatment, which could potentially stabilize or even improve the lung disease, also avoiding the development of other clinical features associated with the condition. The objective of this review is to describe the clinical, serological and radiological features associated with IIM-ILD, mainly focusing on dermatomyositis and antisynthetase syndrome.
间质性肺病（ILD）是特发性炎性肌病（IIM）最常见的死亡原因之一。尽管这些病症通常与近端肌无力、皮疹和关节炎相关，但在高达60%的患者中，ILD可能是首发或唯一的临床特征，这可能导致误诊。早期识别ILD患者潜在的IIM能够实现及时治疗，这有可能稳定甚至改善肺部疾病，还能避免出现与该病症相关的其他临床特征。本综述的目的是描述与IIM-ILD相关的临床、血清学和放射学特征，主要聚焦于皮肌炎和抗合成酶综合征。
Zotero 插件