Alfieri Michele, Principi Samuele, Barbarossa Alessandro, Stronati Giulia, Antonicelli Roberto, Casella Michela, Dello Russo Antonio, Guerra Federico
Department of Biomedical Sciences and Public Health, Marche Polytechnic University, 60131 Ancona, Italy.
Cardiology Unit IRCCS INRCA, Via della Montagnola 81, 60127 Ancona, Italy.
J Clin Med. 2025 Jan 22;14(3):695. doi: 10.3390/jcm14030695.
Left ventricular hypertrabeculation is one of the most debated conditions in modern cardiology. Many studies have tried to characterise this disease by addressing the various clinical risks and diagnostic tools, but its very nosological existence is currently being challenged. The latest ESC guidelines on cardiomyopathies state that it should be addressed as a morphologic trait rather than an intrinsic disease of the cardiac muscle. Despite the huge number of diagnostic criteria and possible phenocopies, no specific consensus identifies a specific flowchart regarding the management of patients with suspected hypertrabeculation. This review aims to provide a clinical approach for patients with a phenotypical appearance of excessive trabeculation.
左心室肌小梁增多是现代心脏病学中争议最大的病症之一。许多研究试图通过探讨各种临床风险和诊断工具来描述这种疾病，但目前其疾病分类学上的存在正受到挑战。欧洲心脏病学会（ESC）最新的心肌病指南指出，应将其视为一种形态学特征，而非心肌的内在疾病。尽管有大量的诊断标准和可能的表型相似疾病，但对于疑似肌小梁增多患者的管理，尚无特定共识确定具体的流程。本综述旨在为具有肌小梁过度增多表型的患者提供一种临床处理方法。
