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一种新型气道清理医疗设备。

A Novel Medical Device for Airway Clearance.

作者信息

Helper Nir, Ashkenazi Moshe, Sokol Gil, Dagan Adi, Efrati Ori

机构信息

Pediatric Pulmonology and National CF Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat Gan 5262000, Israel.

Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.

出版信息

J Clin Med. 2025 Jan 30;14(3):907. doi: 10.3390/jcm14030907.

Abstract

: Airway clearance techniques are a key element in the daily treatment of people with bronchiectasis. There are several methods and devices to assist in effective airway clearance. We investigated LibAirty, a novel medical device, and compared it with the common practice performed today. : Twenty adults enrolled, and each one had three different treatments in a randomized order: a human respiratory physiotherapist, a High-Frequency Chest Wall Oscillator, and LibAirty with BiPAP. The outcome parameters were mucus weight and a questionnaire. Further studies were performed to investigate LibAirty with hypertonic saline (HS) inhalation and using the device as a standalone. : No adverse events were recorded. The sputum amount expectorated in all arms using LibAirty was 14.4 ± 11.1 g with BIPAP, 16.4 ± 7 g with HS, and 11.3 ± 4.1 g for the standalone treatment. For HFCWO, 4.45 ± 3.28 g was obtained, and for CPT, 15.9 ± 11.1 g was obtained. The amount obtained by LibAirty (all arms) was significantly higher than HFCWO. : All arms of LibAirty were superior to HFCWO and similar to the human physiotherapist. Further studies should be performed to investigate the long-term effects of LibAirty.

摘要

气道廓清技术是支气管扩张症患者日常治疗的关键要素。有多种方法和设备可协助进行有效的气道廓清。我们对一种新型医疗设备LibAirty进行了研究,并将其与当前的常规治疗方法进行了比较。:招募了20名成年人,每人按随机顺序接受三种不同的治疗:由人类呼吸物理治疗师进行治疗、使用高频胸壁振荡仪以及使用带有双水平气道正压通气(BiPAP)的LibAirty。观察指标为痰液重量和一份问卷。还进行了进一步的研究,以探究使用LibAirty联合高渗盐水(HS)吸入的情况以及将该设备作为单一治疗手段的效果。:未记录到不良事件。使用LibAirty且搭配BiPAP时,所有组咳出的痰量为14.4±11.1克,搭配HS时为16.4±7克,单一治疗时为11.3±4.1克。使用高频胸壁振荡仪(HFCWO)时咳出4.45±3.28克,使用胸部物理治疗(CPT)时咳出15.9±11.1克。LibAirty(所有组)咳出的痰量显著高于HFCWO。:LibAirty的所有组均优于HFCWO,且与人类物理治疗师的治疗效果相似。应开展进一步研究以探究LibAirty的长期效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6208/11818876/b0f2ce27a6ab/jcm-14-00907-g001.jpg

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