Helper Nir, Ashkenazi Moshe, Sokol Gil, Dagan Adi, Efrati Ori
Pediatric Pulmonology and National CF Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel-Hashomer, Ramat Gan 5262000, Israel.
Faculty of Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.
J Clin Med. 2025 Jan 30;14(3):907. doi: 10.3390/jcm14030907.
: Airway clearance techniques are a key element in the daily treatment of people with bronchiectasis. There are several methods and devices to assist in effective airway clearance. We investigated LibAirty, a novel medical device, and compared it with the common practice performed today. : Twenty adults enrolled, and each one had three different treatments in a randomized order: a human respiratory physiotherapist, a High-Frequency Chest Wall Oscillator, and LibAirty with BiPAP. The outcome parameters were mucus weight and a questionnaire. Further studies were performed to investigate LibAirty with hypertonic saline (HS) inhalation and using the device as a standalone. : No adverse events were recorded. The sputum amount expectorated in all arms using LibAirty was 14.4 ± 11.1 g with BIPAP, 16.4 ± 7 g with HS, and 11.3 ± 4.1 g for the standalone treatment. For HFCWO, 4.45 ± 3.28 g was obtained, and for CPT, 15.9 ± 11.1 g was obtained. The amount obtained by LibAirty (all arms) was significantly higher than HFCWO. : All arms of LibAirty were superior to HFCWO and similar to the human physiotherapist. Further studies should be performed to investigate the long-term effects of LibAirty.
气道廓清技术是支气管扩张症患者日常治疗的关键要素。有多种方法和设备可协助进行有效的气道廓清。我们对一种新型医疗设备LibAirty进行了研究,并将其与当前的常规治疗方法进行了比较。:招募了20名成年人,每人按随机顺序接受三种不同的治疗:由人类呼吸物理治疗师进行治疗、使用高频胸壁振荡仪以及使用带有双水平气道正压通气(BiPAP)的LibAirty。观察指标为痰液重量和一份问卷。还进行了进一步的研究,以探究使用LibAirty联合高渗盐水(HS)吸入的情况以及将该设备作为单一治疗手段的效果。:未记录到不良事件。使用LibAirty且搭配BiPAP时,所有组咳出的痰量为14.4±11.1克,搭配HS时为16.4±7克,单一治疗时为11.3±4.1克。使用高频胸壁振荡仪(HFCWO)时咳出4.45±3.28克,使用胸部物理治疗(CPT)时咳出15.9±11.1克。LibAirty(所有组)咳出的痰量显著高于HFCWO。:LibAirty的所有组均优于HFCWO,且与人类物理治疗师的治疗效果相似。应开展进一步研究以探究LibAirty的长期效果。