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有色人种皮肤肢端黑色素瘤:当前见解与未来方向:一篇叙述性综述

Acral Melanoma in Skin of Color: Current Insights and Future Directions: A Narrative Review.

作者信息

Nadelmann Emily R, Singh Ajay K, Abbruzzese Matteo, Adeuyan Oluwaseyi O, Kenchappa Divya B, Kovrizhkin Katherine, Lightman Michelle, Samouha Avishai, Tao Kevin L, Yun Jaewon, Zhu Tian R, McLellan Beth N, Saenger Yvonne M

机构信息

Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Department of Oncology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

出版信息

Cancers (Basel). 2025 Jan 30;17(3):468. doi: 10.3390/cancers17030468.

DOI:10.3390/cancers17030468
PMID:39941835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11816340/
Abstract

Acral melanoma (AM), also known as acral lentiginous melanoma (ALM), is a rare subtype of melanoma that predominantly occurs on the palms, soles, and nail beds (Figure 1) [...].

摘要

肢端黑色素瘤(AM),也称为肢端雀斑样痣黑色素瘤(ALM),是一种罕见的黑色素瘤亚型,主要发生在手掌、脚底和甲床(图1)[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57c4/11816340/fd8f688ee735/cancers-17-00468-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57c4/11816340/8d536bbd8588/cancers-17-00468-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57c4/11816340/fd8f688ee735/cancers-17-00468-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57c4/11816340/8d536bbd8588/cancers-17-00468-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57c4/11816340/fd8f688ee735/cancers-17-00468-g002.jpg

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Acral Melanoma in Skin of Color: Current Insights and Future Directions: A Narrative Review.有色人种皮肤肢端黑色素瘤:当前见解与未来方向:一篇叙述性综述
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引用本文的文献

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Acral lentiginous melanoma demonstrates more aggressive pathological features than non-acral melanoma in Jamaica: A 10-year multicenter study.肢端雀斑样痣黑色素瘤比牙买加非肢端黑色素瘤表现出更具侵袭性的病理特征:一项为期10年的多中心研究。
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2
Correction: Nadelmann et al. Acral Melanoma in Skin of Color: Current Insights and Future Directions: A Narrative Review. 2025, , 468.更正:纳德尔曼等人。有色人种皮肤中的肢端黑色素瘤:当前见解与未来方向:一篇叙述性综述。2025年,第468页。
Cancers (Basel). 2025 Jul 25;17(15):2458. doi: 10.3390/cancers17152458.
3

本文引用的文献

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Genomic characterization reveals distinct mutational landscape of acral melanoma in East Asian.基因组特征揭示了东亚地区肢端黑色素瘤独特的突变图谱。
J Genet Genomics. 2025 Apr;52(4):525-538. doi: 10.1016/j.jgg.2024.12.018. Epub 2025 Jan 9.
2
Impact of personalized response-directed surgery and adjuvant therapy on survival after neoadjuvant immunotherapy in stage III melanoma: Comparison of 3-year data from PRADO and OpACIN-neo.个性化反应导向手术及辅助治疗对Ⅲ期黑色素瘤新辅助免疫治疗后生存的影响:PRADO和OpACIN-neo研究3年数据比较
Eur J Cancer. 2025 Jan;214:115141. doi: 10.1016/j.ejca.2024.115141. Epub 2024 Nov 19.
3
A Comprehensive Review of the Role of UV Radiation in Photoaging Processes Between Different Types of Skin.
不同类型皮肤中紫外线辐射在光老化过程中作用的综合综述
Cureus. 2025 Mar 24;17(3):e81109. doi: 10.7759/cureus.81109. eCollection 2025 Mar.
Genetic Characteristics of Cutaneous, Acral, and Mucosal Melanoma in Japan.
日本皮肤、肢端和黏膜黑色素瘤的遗传特征。
Cancer Med. 2024 Nov;13(22):e70360. doi: 10.1002/cam4.70360.
4
The genetic evolution of acral melanoma.肢端黑色素瘤的遗传进化。
Nat Commun. 2024 Jul 21;15(1):6146. doi: 10.1038/s41467-024-50233-z.
5
Trends by race and ethnicity in incidence and mortality of acral lentiginous melanoma: analysis of Surveillance, Epidemiology, and End Results 2000-2020.肢端黑色素瘤发病率和死亡率的种族和民族趋势:2000-2020 年监测、流行病学和最终结果分析。
Arch Dermatol Res. 2024 Jul 5;316(7):456. doi: 10.1007/s00403-024-03167-x.
6
Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma.新辅助纳武利尤单抗和伊匹单抗治疗可切除 III 期黑色素瘤。
N Engl J Med. 2024 Nov 7;391(18):1696-1708. doi: 10.1056/NEJMoa2402604. Epub 2024 Jun 2.
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Multidisciplinary approach and treatment of acral and mucosal melanoma.肢端和黏膜黑色素瘤的多学科治疗方法
Front Oncol. 2024 Feb 26;14:1340408. doi: 10.3389/fonc.2024.1340408. eCollection 2024.
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Management of acral lentiginous melanoma: current updates and future directions.肢端雀斑样痣黑色素瘤的管理:当前进展与未来方向
Front Oncol. 2024 Feb 8;14:1323933. doi: 10.3389/fonc.2024.1323933. eCollection 2024.
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Community-engaged education and evaluation of an acral lentiginous melanoma awareness initiative.社区参与的肢端雀斑样痣黑色素瘤认识倡议的教育与评估
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Recent advancements in the diagnosis and treatment of acral melanoma.肢端黑色素瘤的诊断和治疗新进展。
J Zhejiang Univ Sci B. 2024 Feb 15;25(2):106-122. doi: 10.1631/jzus.B2300221.