Zimina L N
Arkh Patol. 1985;47(2):44-51.
Clinical and morphologic analysis of material from 39 patients who died from the myorenal syndrome is given. It is shown that during last 10 years the mortality rate from this syndrome is markedly reduced from 55 to 14% due to new active methods of detoxication. The main morphologic manifestations of the syndrome remain the skeletal muscles necrosis and hemoglobinuric nephrosis leading to acute renal failure. The author describes morphologic, histochemical and electron microscopic features of these lesions. It is noted also that progress in the treatment changed the whole structure of mortality, and the role of new complications, mainly septicemia, was increased. The sources of septicemia are both skin and muscles lesions and catheters and shunts used in modern methods of treatment.
本文给出了对39例死于肌肾综合征患者的材料进行的临床和形态学分析。结果表明,在过去10年中,由于新的有效解毒方法,该综合征的死亡率从55%显著降至14%。该综合征的主要形态学表现仍然是骨骼肌坏死和血红蛋白尿性肾病,进而导致急性肾衰竭。作者描述了这些病变的形态学、组织化学和电子显微镜特征。还指出,治疗方面的进展改变了死亡的整体结构,新并发症(主要是败血症)的作用有所增加。败血症的来源既有皮肤和肌肉病变,也有现代治疗方法中使用的导管和分流器。