Senianskaia N L
Arkh Patol. 1985;47(2):58-65.
The blood of patients dying suddenly possess the capacity of coagulation in vitro and then of transforming spontaneously into a liquid state, this being explained by the post-mortem fibrinolysis. Electron microscopic examination of this process allowed one to follow the dynamics of structural changes in the postmortem coagulates in the course of their spontaneous lysis and retraction in vitro. It is established that the main morphological criterion of the coagulates lysis is the destruction of fibrin fibrils and their degradation into the globular particles. Polynuclear leucocytes play an important role in the lysis of coagulates; they not only phagocytized the aggregated platelets and fibrin but seemed to release specific fibrinolytic factors into the coagulates. In the coagulates undergoing retraction, as distinct from those undergoing lysis, the destruction of platelet aggregates, strengthening and densening of the fibrin network are noted.
突然死亡患者的血液在体外具有凝固能力，随后能自发转变为液态，这可由死后纤溶来解释。对这一过程进行电子显微镜检查，使人们能够追踪死后凝块在体外自发溶解和回缩过程中结构变化的动态。已确定凝块溶解的主要形态学标准是纤维蛋白原纤维的破坏及其降解为球状颗粒。多核白细胞在凝块溶解中起重要作用；它们不仅吞噬聚集的血小板和纤维蛋白，而且似乎向凝块中释放特定的纤溶因子。与正在溶解的凝块不同，正在回缩的凝块中可观察到血小板聚集体的破坏、纤维蛋白网络的强化和致密化。
