Wang Xiao-Xiao, Xu Ying, Song Yan-Feng, Zheng Xiao-Hua, Jiang Xiao-Xiang, Lin Chao-Qin
Department of Obstetrics and Gynecology, Fujian Maternity and Child Health Hospital, 18 Dao-Shan Road, Fuzhou, 350108, Fujian, China.
Department of Obstetrics and Gynecology, the 900th Hospital of Joint Logistic Support Force, Fuzhou, Fujian, China.
Int Urogynecol J. 2025 Feb 13. doi: 10.1007/s00192-025-06065-6.
This study was aimed at comparing the efficacy of different modes of transvaginal temperature-controlled radiofrequency (TTCRF) in improving female stress urinary incontinence (SUI).
A randomized trial with a nested prospective cohort included 89 women with SUI, who were randomized into a unipolar group (n = 35) and a comprehensive group (n = 54). The comprehensive mode group was treated with unipolar and bipolar combination therapy. The 1-h pad test (1-h PWT) was used as the primary metric by which to gauge improvement of SUI. The effective rate was defined as (cure + improvement cases/total cases) × 100%. Daily leakage episodes and urinary incontinence questionnaires were also documented to compliment this metric in assessing treatment efficacy. Patient satisfaction was assessed and adverse reactions were monitored.
No significant difference in the effective rate between the unipolar and comprehensive groups was observed at 1, 3, 6, and 12 months after the end of treatment (62.9% vs 66.7%, 68.6% vs 68.5%, 80.0% vs 71.7%, 74.3% vs 62.5% respectively). Objective improvement of SUI symptoms and subjective satisfaction for all SUI patients were achieved after TTCRF treatment. Ten-course treatment of TTCRF achieved significantly greater treatment effects than five-course treatment as measured by 1-h PWT, daily leakage episodes, International Consultation on Incontinent Questionnaire-Short Form, and Pelvic Organ Prolapsed-Urinary Incontinence Sexual Questionnaire-12. No significant side effects occurred in any patients during treatment.
We consider TTCRF treatment to be a viable outpatient option for SUI, with unipolar and comprehensive modes both showing similar efficacy for SUI.
本研究旨在比较不同模式的经阴道温控射频（TTCRF）改善女性压力性尿失禁（SUI）的疗效。
一项嵌套前瞻性队列随机试验纳入了89例SUI女性患者，将其随机分为单极组（n = 35）和综合组（n = 54）。综合模式组采用单极和双极联合治疗。1小时护垫试验（1-h PWT）作为衡量SUI改善情况的主要指标。有效率定义为（治愈 + 改善病例数/总病例数）×100%。还记录了每日漏尿次数和尿失禁问卷，以辅助该指标评估治疗效果。评估患者满意度并监测不良反应。
治疗结束后1、3、6和12个月，单极组和综合组的有效率无显著差异（分别为62.9%对66.7%、68.6%对68.5%、80.0%对71.7%、74.3%对62.5%）。TTCRF治疗后，所有SUI患者的SUI症状客观改善且主观满意度良好。通过1-h PWT、每日漏尿次数、国际尿失禁咨询委员会简表和盆腔器官脱垂-尿失禁-性功能问卷-12评估，TTCRF十疗程治疗的效果显著优于五疗程治疗。治疗期间所有患者均未出现明显副作用。
我们认为TTCRF治疗是SUI可行的门诊治疗选择，单极和综合模式对SUI的疗效相似。
