辣根过氧化物酶对NAD二聚体的氧化作用。
Oxidation of NAD dimers by horseradish peroxidase.
作者信息
Avigliano L, Carelli V, Casini A, Finazzi-Agrò A, Liberatore F
出版信息
Biochem J. 1985 Mar 1;226(2):391-5. doi: 10.1042/bj2260391.
Abstract
Horseradish peroxidase catalyses the oxidation of NAD dimers, (NAD)2, to NAD+ in accordance with a reaction that is pH-dependent and requires 1 mol of O2 per 2 mol of (NAD)2. Horseradish peroxidase also catalyses the peroxidation of (NAD)2 to NAD+. In contrast, bacterial NADH peroxidase does not catalyse the peroxidation or the oxidation of (NAD)2. A free-radical mechanism is proposed for both horseradish-peroxidase-catalysed oxidation and peroxidation of (NAD)2.
摘要
辣根过氧化物酶催化NAD二聚体（NAD）2氧化为NAD+，该反应依赖于pH值，每2摩尔（NAD）2需要1摩尔O2。辣根过氧化物酶还催化（NAD）2的过氧化反应生成NAD+。相比之下，细菌NADH过氧化物酶不催化（NAD）2的过氧化或氧化反应。有人提出了一种自由基机制来解释辣根过氧化物酶催化的（NAD）2氧化和过氧化反应。
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