[血红蛋白氧合作用的有机磷调节剂的合成与性质]
[Synthesis and properties of an organophosphorous regulator of hemoglobin oxygenation].
作者信息
Ushakova I P, Tuvin M Iu, Serebrennikova G A, Kol'tsova G N, Viazova E P
出版信息
Bioorg Khim. 1985 Feb;11(2):187-91.
PMID:3994772
Abstract
Racemic 1-O-(epsilon-aminohexanoyl)-2,3-diphosphoglycerol (ADPG) was synthesized. The pH dependence of the 31P-NMR spectra was studied for the ADPG cyclohexylammonium salt. ADPG binding to hemoglobin and its functional activity as a regulator of human hemoglobin reversible oxygenation were assayed.
摘要
合成了外消旋1 - O -（ε-氨基己酰基）- 2,3 -二磷酸甘油（ADPG）。研究了ADPG环己铵盐的31P - NMR谱的pH依赖性。测定了ADPG与血红蛋白的结合及其作为人血红蛋白可逆氧合调节剂的功能活性。
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