[可逆性血红蛋白氧合调节剂——二醇双磷酸酯的合成与分析]
[Synthesis and analysis of glycol bis-phosphates, regulators of reversible hemoglobin oxygenation].
作者信息
Chuvilin A N, Serebrennikova G A, Evstigneeva R P, Kol'tsova G N, Viazova E P
出版信息
Bioorg Khim. 1985 Jun;11(6):845-8.
PMID:4038353
Abstract
Bisphosphates of glycols, ethyleneglycol and 1,2-propanediol, were synthesized. These structural analogues of 2,3-diphosphoglyceric acid were shown to reduce significantly the oxygen affinity of stripped hemoglobin.
摘要
合成了二醇、乙二醇和1,2 -丙二醇的双磷酸盐。这些2,3 -二磷酸甘油酸的结构类似物被证明能显著降低脱辅基血红蛋白的氧亲和力。
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