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下颌骨前部骨软骨瘤:一例罕见病例报告及文献复习

Osteochondroma of the anterior mandible: A rare case report and review of the literature.

作者信息

Palve Devendra H, Dhobley Akshay A, Ghatage Dipak D, Kendre Ashwini G

机构信息

Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Nagpur, Maharashtra, India.

出版信息

J Oral Maxillofac Pathol. 2024 Oct-Dec;28(4):672-676. doi: 10.4103/jomfp.jomfp_37_24. Epub 2024 Dec 31.

DOI:10.4103/jomfp.jomfp_37_24
PMID:39949685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11819633/
Abstract

Osteochondroma (OC) is the most common benign tumour of the axial skeleton which often occurs from the metaphysis of the long bones but rarely occurs in the craniofacial region (<1% of cases). Literature shows that cases occur more in the mandibular condylar region. To date, only six cases of this incredibly rare OC in the mandibular front region have been documented in the last 30 years. In addition to reviewing the literature on OCs of the mandibular front region, this case report describes a case of OC involving the mandibular symphysis and left para-symphysis in a 67-year-old male patient. Histopathological examination revealed chondroid and osteoid tissue with sparse fibrous tissue patches and columns of chondrocytes with single tiny nuclei within the cartilaginous cap, and all these features were strongly suggestive of OC diagnosis.

摘要

骨软骨瘤(OC)是中轴骨骼最常见的良性肿瘤,常发生于长骨的干骺端,但很少发生在颅面部区域(<1%的病例)。文献表明,病例更多发生在下颌髁突区域。迄今为止,在过去30年中仅记录了6例下颌前部区域这种极其罕见的骨软骨瘤病例。除了回顾有关下颌前部区域骨软骨瘤的文献外,本病例报告还描述了一例67岁男性患者发生在下颌联合和左侧旁联合处的骨软骨瘤病例。组织病理学检查显示软骨样和骨样组织,伴有稀疏的纤维组织斑块,软骨帽内有单核小软骨细胞柱,所有这些特征都强烈提示骨软骨瘤的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/d1b641fcd7d5/JOMFP-28-672-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/3d5979e3e4e9/JOMFP-28-672-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/3c2bccff6018/JOMFP-28-672-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/0de781e8496b/JOMFP-28-672-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/37343dcb8e7a/JOMFP-28-672-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/d1b641fcd7d5/JOMFP-28-672-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/3d5979e3e4e9/JOMFP-28-672-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/3c2bccff6018/JOMFP-28-672-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/0de781e8496b/JOMFP-28-672-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/37343dcb8e7a/JOMFP-28-672-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8a7/11819633/d1b641fcd7d5/JOMFP-28-672-g005.jpg

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本文引用的文献

1
Osteochondroma of the coronoid process: A case report and review of the literature.冠状突骨软骨瘤:一例病例报告及文献复习
Oncol Lett. 2019 Sep;18(3):2270-2277. doi: 10.3892/ol.2019.10537. Epub 2019 Jun 27.
2
Osteochondroma condyle: A journey of 20 years in a 52-year-old male patient causing severe facial asymmetry and occlusal derangement.髁突骨软骨瘤:一名52岁男性患者20年的病程,导致严重面部不对称和咬合紊乱。
J Oral Maxillofac Pathol. 2019 Jan-Apr;23(1):162. doi: 10.4103/jomfp.JOMFP_136_17.
3
Giant osteochondroma of the coronoid process.
冠状突巨大骨软骨瘤
J Maxillofac Oral Surg. 2015 Mar;14(Suppl 1):412-6. doi: 10.1007/s12663-014-0650-8. Epub 2014 Jul 8.
4
Nonodontogenic mandibular lesions: differentiation based on CT attenuation.非牙源性下颌骨病变:基于CT衰减的鉴别诊断
Diagn Interv Radiol. 2014 Nov;20(6):475-80. doi: 10.5152/dir.2014.14143.
5
Osteochondroma of the mandible: a rare case report.下颌骨骨软骨瘤:一例罕见病例报告。
Case Rep Pathol. 2013;2013:167862. doi: 10.1155/2013/167862. Epub 2013 Sep 26.
6
A unique case of multiple osteochondroma: Mandibular symphysis and femur.一例罕见的多发性骨软骨瘤病例:下颌骨联合部和股骨。
Ann Maxillofac Surg. 2012 Jul;2(2):182-4. doi: 10.4103/2231-0746.101356.
7
Secondary chondrosarcoma in the mandibular condyle.下颌骨髁突的继发软骨肉瘤。
Dentomaxillofac Radiol. 2011 Jul;40(5):320-3. doi: 10.1259/dmfr/17575463.
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Review of osteochondroma of mandibular condyle and report of a case series.下颌骨髁突骨软骨瘤的综述及病例系列报告
J Oral Maxillofac Surg. 2011 Nov;69(11):2815-23. doi: 10.1016/j.joms.2010.10.016. Epub 2011 Mar 2.
9
Osteochondroma of the condyle: review of 8 cases.髁突骨软骨瘤 8 例报告
Int J Oral Maxillofac Surg. 2010 Jun;39(6):523-8. doi: 10.1016/j.ijom.2010.02.015. Epub 2010 Mar 25.
10
Osteochondromas of the mandibular condyle: variance in radiographic appearance on panoramic radiographs.下颌髁突骨软骨瘤:全景X线片上的影像学表现差异
Dentomaxillofac Radiol. 2008 Mar;37(3):154-60. doi: 10.1259/dmfr/19168643.