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微创脊柱手术在脊柱肿瘤学中的作用

Role of Minimally Invasive Spine Surgery in Spine Oncology.

作者信息

Newman W Christopher, Bilsky Mark H, Barzilai Ori

机构信息

Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

出版信息

Neurosurgery. 2025 Mar 1;96(3S):S119-S128. doi: 10.1227/neu.0000000000003340. Epub 2025 Feb 14.

Abstract

The application of minimally invasive spine surgery (MISS) in degenerative spine disease and deformity has seen rapid growth in the past 20 years. Building on this experience, such methods have been adopted into spine oncology in the past decade, particularly for metastatic disease. The impetus for this growth stems from the benefits of surgical decompression combined with radiation treatment in patients with metastatic disease in conjunction with the need for less morbid interventions in a patient population with limited life expectancy. The result of these two realizations was the application of minimally invasive techniques for the treatment of spine tumors including re-establishment of spinal stability, decompression of the spinal cord or nerve roots, and restoration of spinal alignment. Technological advancement and improvement in biomaterials have allowed for durable stabilization with short constructs even for patients with poor bone quality. The implementation of navigation and robotic capabilities has transformed MISS by streamlining surgery and further reducing the surgical footprint while laser ablation, endoscopy, and robotic surgery hold the potential to minimize the surgical footprint even further. MISS for intradural tumors is commonly performed, while the role for other primary tumors has yet to be defined. In this article, we describe the evolution of and indications for MISS in spine oncology through a retrospective literature review.

摘要

在过去20年里,微创脊柱手术(MISS)在退行性脊柱疾病和脊柱畸形中的应用迅速增长。基于这一经验,在过去十年中,此类方法已被应用于脊柱肿瘤学领域,尤其是转移性疾病。这种增长的动力源于手术减压联合放射治疗对转移性疾病患者的益处,以及在预期寿命有限的患者群体中对低创伤干预措施的需求。这两点促成了微创技术在脊柱肿瘤治疗中的应用,包括重建脊柱稳定性、减压脊髓或神经根以及恢复脊柱排列。技术进步和生物材料的改进使得即使对于骨质较差的患者,也能用短节段内固定实现持久稳定。导航和机器人技术的应用改变了微创脊柱手术,简化了手术流程,进一步缩小了手术切口,而激光消融、内窥镜检查和机器人手术甚至有潜力进一步减小手术切口。硬膜内肿瘤的微创脊柱手术已普遍开展,而其他原发性肿瘤的应用尚未明确。在本文中,我们通过回顾性文献综述描述了脊柱肿瘤学中微创脊柱手术的发展历程和适应证。

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