Chen Zhongda, Song Jun, Lu Yu, Zhu Jing, Zhu Hongxu, Du Wenxian, Hu Benhui
School of Biomedical Engineering and Informatics, Nanjing Medical University, 101 Longmian Avenue, Nanjing, 211166, China.
Materdicine Lab, School of Life Sciences, Shanghai University, 99 Shangda Road, Shanghai, 200444, China.
Adv Sci (Weinh). 2025 Apr;12(14):e2415608. doi: 10.1002/advs.202415608. Epub 2025 Feb 14.
Wearable electronics can achieve high-fidelity monitoring of pulse waveforms on the body surface enabling early diagnosis of cardiovascular diseases (CVDs). Textile-based wearable devices offer advantages in terms of high permeability and comfort. However, knitted strain sensors struggle to capture small-range deformation signals due to stress dissipation during friction and slip of yarns within the textiles. They are optimized for mechanical adaptability and adhesive capability. In this work, the stitch configurations of knitted structure are adjusted to optimize the energy dissipation ratio during deformation and waveform fitting performance. These electric-mechanical results enabled the selection of the most suitable knitted structure for the clinical diagnosis. On the other hand, the sensor's adhesion is optimized with respect to electrical-force-strain coupling and energy transfer efficiency at the interface between skin and sensor. The balance between the storage modulus and loss modulus are adjusted via the crosslinking degree of the polyacrylamide (PAAm) hydrogel network. As a result, the optimized knitted sensor enables stable collection of pulse waveforms from the radial and dorsalis pedis arteries. In human patient evaluations, the knitting-based strain sensor can distinguish patients with different potential CVD risks through extracted characteristic indicators.
可穿戴电子产品能够对体表脉搏波形进行高保真监测,从而实现心血管疾病(CVD)的早期诊断。基于纺织品的可穿戴设备在高透气性和舒适性方面具有优势。然而,由于纺织品内部纱线在摩擦和滑动过程中的应力耗散,针织应变传感器难以捕捉小范围的变形信号。它们针对机械适应性和粘附能力进行了优化。在这项工作中,调整了针织结构的针脚配置,以优化变形过程中的能量耗散率和波形拟合性能。这些机电结果有助于选择最适合临床诊断的针织结构。另一方面,针对皮肤与传感器界面处的电力 - 应变耦合和能量传递效率,对传感器的粘附性进行了优化。通过调整聚丙烯酰胺(PAAm)水凝胶网络的交联度来平衡储能模量和损耗模量。结果,优化后的针织传感器能够稳定地采集桡动脉和足背动脉的脉搏波形。在人体患者评估中,基于针织的应变传感器可以通过提取的特征指标区分具有不同潜在心血管疾病风险的患者。