正电子发射断层扫描/计算机断层扫描在胃肠道恶性肿瘤放射肿瘤学中的作用进展
Updates in the Role of Positron Emission Tomography/Computed Tomography in Radiation Oncology in Gastrointestinal Malignancies.
作者信息
Kumar Ritesh, Shalaby Ahmed, Narra Lakshmi Rekha, Gokhale Shivani, Deek Matthew P, Jabbour Salma K
机构信息
Department of Radiation Oncology, Rutgers Cancer Institute, Rutgers Robert Wood Johnson Medical School, Rutgers University, 195 Little Albany Street, New Brunswick, NJ 08901, USA.
Department of Radiation Oncology, Rutgers Cancer Institute, Rutgers Robert Wood Johnson Medical School, Rutgers University, 195 Little Albany Street, New Brunswick, NJ 08901, USA.
出版信息
PET Clin. 2025 Apr;20(2):219-229. doi: 10.1016/j.cpet.2025.01.004. Epub 2025 Feb 13.
Positron Emission Tomography/Computed Tomography (PET/CT) plays a critical role in managing gastrointestinal (GI) cancers within radiation oncology. It enhances tumor detection, staging, and lymph node involvement assessment, leading to better-targeted radiation treatment. PET/CT also aids in delineating tumor volumes to minimize geographic misses, enabling precise dose escalation to metabolically active regions. Despite its benefits, PET/CT has limitations such as false positives and dependency on complementary imaging. Emerging technologies offer real-time adjustments and personalized treatments, advancing precision medicine in GI radiation oncology. Further research is needed to refine PET/CT integration for improved treatment outcomes and cost-effectiveness.
正电子发射断层扫描/计算机断层扫描（PET/CT）在放射肿瘤学中对胃肠道（GI）癌症的管理起着关键作用。它可提高肿瘤检测、分期及淋巴结受累评估的准确性，从而实现更有针对性的放射治疗。PET/CT还有助于勾勒肿瘤体积，以尽量减少区域遗漏，从而能够精确地增加对代谢活跃区域的剂量。尽管有这些优点，但PET/CT也存在局限性，如假阳性以及对补充成像的依赖性。新兴技术可实现实时调整和个性化治疗，推动了胃肠道放射肿瘤学中的精准医学发展。需要进一步研究以优化PET/CT的整合，从而改善治疗效果和成本效益。
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