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比生群用于晚期尿路上皮恶性肿瘤的实验研究及II期试验。

Experimental studies and phase II trial of bisantrene in advanced urothelial malignancies.

作者信息

Scher H I, Ahmed T, Yagoda A, Kyriazis A P, Watson R C

出版信息

Cancer Invest. 1985;3(2):123-7. doi: 10.3109/07357908509017495.

DOI:10.3109/07357908509017495
PMID:3995377
Abstract

A phase II trial with bisantrene was performed simultaneously against urothelial tumors in nude mice and in patients with metastatic transitional cell carcinoma. The starting dose was 260 mg/m2, intravenously, every 3 weeks. No responses were seen in the in vivo animal study or in 13 treated patients.

摘要

一项关于双胺苯吖啶的II期试验同时在裸鼠的尿路上皮肿瘤以及转移性移行细胞癌患者中开展。起始剂量为260mg/m²,静脉注射,每3周一次。在体内动物研究以及13例接受治疗的患者中均未观察到反应。

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