Hosseinikebria Somayeh, Khazaei Masoud, Dervisevic Muamer, Judicpa Mia Angela, Tian Junfei, Razal Joselito M, Voelcker Nicolas Hans, Nilghaz Azadeh
Institute for Frontier Materials, Deakin University, Waurn Ponds, VIC 3216, Australia.
Drug Delivery, Disposition, and Dynamics, Monash University, Parkville, VIC 3052, Australia; Melbourne Centre for Nanofabrication, Victorian Node of the Australian National Fabrication Facility, Clayton, Victoria 3168, Australia.
Food Chem. 2025 May 30;475:143284. doi: 10.1016/j.foodchem.2025.143284. Epub 2025 Feb 9.
Electrochemical biosensors transduce chemical reactions into measurable electrical signals by incorporating recognition components. Although they are capable of detecting a broad range of target molecules, their application in complex matrices, such as food, at minimum or no sample preparation, is challenging and requires the introduction of innovative and effective strategies. This review explores the recent advances in electrochemical biosensors for on-site food safety and quality analysis. We first discuss the presence of chemical contaminants and biohazards in food and the need for robust, rapid, low-cost, and point-of-care (POC) analytical techniques. We then address the critical aspects of sensitivity and selectivity of electrochemical biosensors in detecting chemical and biological contaminants in real food samples. We finally investigate the major drawbacks of these biosensors and provide future perspectives on the field.
电化学生物传感器通过整合识别元件将化学反应转化为可测量的电信号。尽管它们能够检测多种目标分子,但在诸如食品等复杂基质中,在最少或无需样品制备的情况下应用具有挑战性,需要引入创新且有效的策略。本综述探讨了用于现场食品安全和质量分析的电化学生物传感器的最新进展。我们首先讨论食品中化学污染物和生物危害的存在以及对强大、快速、低成本和即时检测(POC)分析技术的需求。然后我们阐述电化学生物传感器在检测实际食品样品中的化学和生物污染物时的灵敏度和选择性的关键方面。我们最后研究这些生物传感器的主要缺点并提供该领域的未来展望。