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Resmetirom: Breakthrough therapeutic approach for metabolic dysfunction-associated steatohepatitis.

作者信息

Saeed Anzel, Rai Kuldeep Dalpat, Saeed Muzammil

机构信息

Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.

Department of Medicine, Karachi Medical and Dental College, Karachi Metropolitan University, Karachi, Pakistan.

出版信息

Liver Res. 2024 Jul 14;8(3):193-194. doi: 10.1016/j.livres.2024.07.002. eCollection 2024 Sep.

Abstract
摘要

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A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.
N Engl J Med. 2024 Feb 8;390(6):497-509. doi: 10.1056/NEJMoa2309000.
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Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis.
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Pharmacotherapy for NASH: Current and emerging.
J Hepatol. 2018 Feb;68(2):362-375. doi: 10.1016/j.jhep.2017.10.015. Epub 2017 Nov 6.
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Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention.
Nat Rev Gastroenterol Hepatol. 2018 Jan;15(1):11-20. doi: 10.1038/nrgastro.2017.109. Epub 2017 Sep 20.
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Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease.
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