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Resmetirom: Breakthrough therapeutic approach for metabolic dysfunction-associated steatohepatitis.

作者信息

Saeed Anzel, Rai Kuldeep Dalpat, Saeed Muzammil

机构信息

Department of Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.

Department of Medicine, Karachi Medical and Dental College, Karachi Metropolitan University, Karachi, Pakistan.

出版信息

Liver Res. 2024 Jul 14;8(3):193-194. doi: 10.1016/j.livres.2024.07.002. eCollection 2024 Sep.

DOI:10.1016/j.livres.2024.07.002
PMID:39957747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11771249/
Abstract
摘要

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本文引用的文献

1
Role of Resmetirom, a Liver-Directed, Thyroid Hormone Receptor Beta-Selective Agonist, in Managing Nonalcoholic Steatohepatitis: A Systematic Review and Meta-Analysis.Resmetirom 作为一种肝脏靶向、甲状腺激素受体β选择性激动剂，在治疗非酒精性脂肪性肝炎中的作用：系统评价和荟萃分析。
Endocr Pract. 2024 Jul;30(7):631-638. doi: 10.1016/j.eprac.2024.04.016. Epub 2024 May 1.
2
The effect and safety of obeticholic acid for patients with nonalcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials.熊去氧胆酸治疗非酒精性脂肪性肝炎患者的疗效和安全性：一项系统评价和随机对照试验的荟萃分析。
Medicine (Baltimore). 2024 Feb 16;103(7):e37271. doi: 10.1097/MD.0000000000037271.
3
A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.一项评估 Resmetirom 治疗伴有肝纤维化的 NASH 的 3 期随机对照试验。
N Engl J Med. 2024 Feb 8;390(6):497-509. doi: 10.1056/NEJMoa2309000.
4
Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis.非酒精性脂肪性肝炎的病因、发病机制及治疗
N Engl J Med. 2017 Nov 23;377(21):2063-2072. doi: 10.1056/NEJMra1503519.
5
Pharmacotherapy for NASH: Current and emerging.非酒精性脂肪性肝炎的药物治疗：现状与进展。
J Hepatol. 2018 Feb;68(2):362-375. doi: 10.1016/j.jhep.2017.10.015. Epub 2017 Nov 6.
6
Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention.非酒精性脂肪性肝病和非酒精性脂肪性肝炎的全球负担：趋势、预测、危险因素和预防。
Nat Rev Gastroenterol Hepatol. 2018 Jan;15(1):11-20. doi: 10.1038/nrgastro.2017.109. Epub 2017 Sep 20.
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Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis.非酒精性脂肪性肝病中纤维化阶段导致的死亡风险增加：系统评价与荟萃分析
Hepatology. 2017 May;65(5):1557-1565. doi: 10.1002/hep.29085. Epub 2017 Mar 31.
8
Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease.肝纤维化而非其他组织学特征与非酒精性脂肪性肝病患者的长期预后相关。
Gastroenterology. 2015 Aug;149(2):389-97.e10. doi: 10.1053/j.gastro.2015.04.043. Epub 2015 Apr 29.