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经口内镜下肌切开术(POEM)治疗贲门失弛缓症:两例报告

Peroral Endoscopic Myotomy (POEM) for Achalasia Cardia: A Report of Two Cases.

作者信息

Paudel Mukesh S, Khadka Dibas, Bhattarai Kumud, Basnet Bhupendra K, Agarwal Ashish

机构信息

Gastroenterology, National Academy of Medical Sciences, Kathmandu, NPL.

Gastroenterology, Bir Hospital, National Academy of Medical Sciences, Kathmandu, NPL.

出版信息

Cureus. 2025 Jan 15;17(1):e77467. doi: 10.7759/cureus.77467. eCollection 2025 Jan.

DOI:10.7759/cureus.77467
PMID:39958124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11827286/
Abstract

Achalasia cardia is a motility disorder of the esophagus characterized by a lack of esophageal peristalsis and failure of lower esophageal sphincter opening during swallowing. Symptomatic patients present with a long history of difficulty swallowing, along with chest pain and vomiting. Two male patients, 55 and 24 years old, with proven achalasia cardia by high-resolution esophageal manometry (HRM), underwent a successful peroral endoscopic myotomy (POEM) procedure at our center. This was the first time this procedure was done in Nepal. In this case report, we have demonstrated that a novel third-space procedure like POEM can be safely performed in a resource-limited country.

摘要

贲门失弛缓症是一种食管动力障碍性疾病,其特征为缺乏食管蠕动以及吞咽时食管下括约肌不能开放。有症状的患者有长期吞咽困难病史,伴有胸痛和呕吐。两名男性患者,年龄分别为55岁和24岁,经高分辨率食管测压(HRM)证实为贲门失弛缓症,在我们中心成功接受了经口内镜下肌切开术(POEM)。这是该手术首次在尼泊尔开展。在本病例报告中,我们证明了像POEM这样的新型第三间隙手术能够在资源有限的国家安全实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a919/11827286/7457ad9f9847/cureus-0017-00000077467-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a919/11827286/770ea7f5d2b9/cureus-0017-00000077467-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a919/11827286/e6429cfbf7ee/cureus-0017-00000077467-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a919/11827286/7457ad9f9847/cureus-0017-00000077467-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a919/11827286/770ea7f5d2b9/cureus-0017-00000077467-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a919/11827286/e6429cfbf7ee/cureus-0017-00000077467-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a919/11827286/7457ad9f9847/cureus-0017-00000077467-i03.jpg

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本文引用的文献

1
[Endoscopic Treatment for Esophageal Achalasia:Per-oral Endoscopic Myotomy( POEM)].[内镜治疗食管贲门失弛缓症:经口内镜下肌切开术(POEM)]
Kyobu Geka. 2024 Sep;77(10):896-901.
2
AGA Clinical Practice Update on Advances in Per-Oral Endoscopic Myotomy (POEM) and Remaining Questions-What We Have Learned in the Past Decade: Expert Review.AGA 临床实践更新:经口内镜下肌切开术 (POEM) 的进展和遗留问题——我们在过去十年中学到了什么:专家综述。
Gastroenterology. 2024 Dec;167(7):1483-1490. doi: 10.1053/j.gastro.2024.08.038. Epub 2024 Oct 16.
3
Achalasia Cardia: A Case Series.
贲门失弛缓症:病例系列。
JNMA J Nepal Med Assoc. 2024 Jun 30;62(275):474-477. doi: 10.31729/jnma.8649.
4
Diagnosis and Management of Achalasia: Updates of the Last Two Years.贲门失弛缓症的诊断与管理:过去两年的进展
J Clin Med. 2021 Aug 16;10(16):3607. doi: 10.3390/jcm10163607.
5
Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0.高分辨率食管动力障碍:芝加哥分类版本 4.0。
Neurogastroenterol Motil. 2021 Jan;33(1):e14058. doi: 10.1111/nmo.14058.
6
Characteristics of a Subset of Achalasia With Normal Integrated Relaxation Pressure.具有正常综合松弛压的贲门失弛缓症亚组的特征
J Neurogastroenterol Motil. 2020 Apr 30;26(2):274-280. doi: 10.5056/jnm19130.
7
Endoscopic or Surgical Myotomy in Patients with Idiopathic Achalasia.特发性贲门失弛缓症患者的内镜或手术肌切开术。
N Engl J Med. 2019 Dec 5;381(23):2219-2229. doi: 10.1056/NEJMoa1905380.
8
Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic achalasia.气囊扩张与腹腔镜 Heller 肌切开术治疗特发性贲门失弛缓症。
N Engl J Med. 2011 May 12;364(19):1807-16. doi: 10.1056/NEJMoa1010502.