超声引导下深平面与浅平面连续前锯肌平面阻滞用于多根肋骨骨折患者疼痛管理的前瞻性随机双盲临床试验。

Ultrasound-guided deep versus superficial continuous serratus anterior plane block for pain management in patients with multiple rib fractures: A prospective randomized double-blind clinical trial.

作者信息

Mostafa Mohamed F, Bakr Mohamed Abdel-Moniem, Seddik Mohamed Ismail, Mahmoud Mohammed Mamdouh Mohammed, Ibrahim Gamal M A, Ahmed Ahmed Talaat

机构信息

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Assiut University, Assiut, Egypt.

Department of Clinical Pathology, Faculty of Medicine, Assiut University, Assiut, Egypt.

出版信息

Saudi J Anaesth. 2025 Jan-Mar;19(1):58-64. doi: 10.4103/sja.sja_493_24. Epub 2025 Jan 1.

Abstract

BACKGROUND

Efficient analgesia is the cornerstone in multiple rib fractures (MRFs) management. The serratus anterior plane block (SAPB) shows promising outcomes. However, it is still provocative whether the superficial or deep approach is more effective in the SAPB procedure. We hypothesized that the deep approach of ultrasound (US)-guided continuous SAPB could be superior for MRFs pain management.

METHODS

Sixty-two adult patients having unilateral MRFs, were randomized into two groups to receive continuous superficial SAPB (group S, n = 31) or continuous deep SAPB (group D, n = 31). As a primary outcome, we compared pain numeric rating scale (NRS), while total analgesic consumption, incentive spirometer volume (IS-V), lung ultrasound score (LUSS), basal and 24-h serum beta-endorphin (BE) levels, and any adverse events were secondary outcomes.

RESULTS

There was a significant reduction in NRS in favor of group D when compared to group S at 30 minutes ( = 0.001) until 12 hours ( = 0.029); total analgesic consumption was significantly lower in group D ( = 0.005). A significant increase in the median IS-V in group D compared to group S at 90 minutes ( = 0.02) and 12h postblock ( = 0.004) LUSS was significantly lower in D group at 90 min, 12 h, and 24 h ( = 0.04, 0.001, 0.031). No significant differences as regards serum BE levels. No adverse events were noted.

CONCLUSION

Either superficial or deep continuous SAPB can be used safely and effectively in managing pain related to MRFs. Notably, the deep approach offered superior analgesia and improved deep breathing compared to the superficial.

摘要

背景

有效的镇痛是多发性肋骨骨折(MRF)治疗的基石。前锯肌平面阻滞(SAPB)显示出良好的效果。然而,在SAPB操作中,浅入路或深入路哪种更有效仍存在争议。我们假设超声(US)引导下连续SAPB的深入路在MRF疼痛管理方面可能更具优势。

方法

62例单侧MRF的成年患者被随机分为两组,分别接受连续浅入路SAPB(S组,n = 31)或连续深入路SAPB(D组,n = 31)。作为主要结局指标,我们比较了疼痛数字评定量表(NRS),而总镇痛药物消耗量、激励肺活量计测量的肺活量(IS-V)、肺部超声评分(LUSS)、基础及24小时血清β-内啡肽(BE)水平以及任何不良事件为次要结局指标。

结果

与S组相比,D组在30分钟(P = 0.001)至12小时(P = 0.029)时NRS显著降低;D组的总镇痛药物消耗量显著更低(P = 0.005)。与S组相比,D组在90分钟(P = 0.02)和阻滞后12小时(P = 0.004)时IS-V中位数显著增加;D组在90分钟、12小时和24小时时LUSS显著更低(P = 0.04、0.001、0.031)。血清BE水平无显著差异。未观察到不良事件。

结论

浅入路或深入路连续SAPB均可安全有效地用于管理与MRF相关的疼痛。值得注意的是,与浅入路相比,深入路提供了更好的镇痛效果并改善了深呼吸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9ba/11829691/97e9fa2f549d/SJA-19-58-g001.jpg

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