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电视辅助胸腔镜肺叶切除术中超声引导下深、浅部前锯肌平面阻滞的术中镇痛效果比较:一项前瞻性随机临床试验。

Comparison of the intraoperative analgesic efficacy between ultrasound-guided deep and superficial serratus anterior plane block during video-assisted thoracoscopic lobectomy: A prospective randomized clinical trial.

作者信息

Moon Suyoung, Lee Jungwon, Kim Hyuckgoo, Kim Jeongeun, Kim Jiseob, Kim Saeyoung

机构信息

Department of Anesthesiology and Pain Medicine, School of Medicine, Kyungpook National University.

Department of Anesthesiology and Pain Medicine, Yeungnam University College of Medicine.

出版信息

Medicine (Baltimore). 2020 Nov 20;99(47):e23214. doi: 10.1097/MD.0000000000023214.

Abstract

BACKGROUND

The serratus anterior plane block (SAPB) is a novel method that provides lateral chest wall analgesia. There are 2 methods of SAPB; deep and superficial SAPB. Each of these methods has been demonstrated to provide effective perioperative analgesia in thoracic surgery. The aim of this study was to compare the intraoperative hemodynamic and analgesic benefits of deep versus superficial SAPB during video-assisted thoracic surgery (VATS) lobectomy.

METHODS

We performed a prospective, randomized, patient/assessor-blinded trial. We included patients who were 20 to 75 years of age and scheduled to undergo VATS lobectomy with American Society of Anesthesiologists physical status 1 or 2. Patients were randomly allocated to receive either ultrasound-guided deep SAPB (Group D) or superficial SAPB (Group S). The primary outcome was intraoperative remifentanil consumption. We also recorded intraoperative systolic blood pressure (SBP), heart rate (HR), emergence time, and doses of rescue drugs used to manage hemodynamic instability.

RESULTS

Data for 50 patients undergoing 3-port VATS lobectomy were analyzed. Intraoperative remifentanil consumption did not differ significantly between Group D (n = 25, 715.62 ± 320.36 μg) and group S (n = 25, 721.08 ± 294.48 μg) (P = .97). Additionally, there were no significant differences between the 2 groups in SBP and HR at any time point, emergence time, or amount of rescue drugs used.

CONCLUSION

Our study suggests that the intraoperative analgesic efficacy is similar for deep and superficial SAPB during VATS lobectomy.

摘要

背景

前锯肌平面阻滞(SAPB)是一种提供胸壁外侧镇痛的新方法。SAPB有两种方法:深部和浅部SAPB。已证明每种方法在胸外科手术中均能提供有效的围手术期镇痛。本研究的目的是比较电视辅助胸腔镜手术(VATS)肺叶切除术中深部与浅部SAPB在术中血流动力学和镇痛方面的益处。

方法

我们进行了一项前瞻性、随机、患者/评估者双盲试验。纳入年龄在20至75岁之间、计划接受美国麻醉医师协会身体状况1或2级的VATS肺叶切除术的患者。患者被随机分配接受超声引导下的深部SAPB(D组)或浅部SAPB(S组)。主要结局是术中瑞芬太尼的消耗量。我们还记录了术中收缩压(SBP)、心率(HR)、苏醒时间以及用于处理血流动力学不稳定的抢救药物剂量。

结果

分析了接受三端口VATS肺叶切除术的50例患者的数据。D组(n = 25,715.62±320.36μg)和S组(n = 25,721.08±294.48μg)术中瑞芬太尼消耗量差异无统计学意义(P = 0.97)。此外,两组在任何时间点的SBP和HR、苏醒时间或抢救药物使用量方面均无显著差异。

结论

我们的研究表明,VATS肺叶切除术中深部和浅部SAPB的术中镇痛效果相似。

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