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2型糖尿病高危成年人的连续和动态血糖监测:一项范围综述

Continuous and Flash Glucose Monitoring in Adults at Risk of Type 2 Diabetes: A Scoping Review.

作者信息

Amoh Prince, Broom David, Kyrou Ioannis, Nartey Samuel, Paul Anna, Esliger Dale, Whelan Maxine

机构信息

Coventry University, Coventry, UK.

University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.

出版信息

J Diabetes Sci Technol. 2025 Feb 17:19322968251315497. doi: 10.1177/19322968251315497.

Abstract

BACKGROUND

Continuous glucose monitoring (CGM) and flash glucose monitoring (FGM) are widely used in diabetes management and increasingly being considered for type 2 diabetes mellitus (T2DM) prevention. This scoping review aims to summarize the literature published to date on CGM and FGM use in adults at risk of T2DM.

METHODS

A systematic search of four databases (CINAHL, PsycINFO, MEDLINE, Cochrane Library) was conducted, covering studies from 1985 to 2024. Eligible studies used CGM or FGM in interventional settings targeting adults at risk of T2DM. Rayyan software facilitated article screening, and the Johns Hopkins Evidence-Based Practice tool assessed study quality.

RESULTS

From 13 644 articles, 12 studies were included, reporting on 1144 participants (353 at-risk, mean age 47 ± 12.8 years) across eight countries. Ten studies employed FGM, focusing on health-related behaviors (diet, physical activity, or both). Significant improvements in glucose control and anthropometrics were reported in 75% and 50% of the studies, respectively, along with reductions in glycated hemoglobin, fasting glucose, and insulin resistance. Seven studies used qualitative methods, with recurrent themes including perceived benefits and motivators for behavior change and acceptability and feasibility of device use. Three studies were rated as "high" level and scored a "B" for evidence quality, while the remaining studies were lower for both level and evidence quality.

CONCLUSIONS

Existing published studies deploying glucose monitoring technologies show promise in supporting interventions aimed at preventing T2DM in at-risk adults. Further robust studies are required to confirm the long-term acceptability and efficacy of these technologies.

摘要

背景

连续血糖监测(CGM)和动态血糖监测(FGM)在糖尿病管理中广泛应用,并且越来越多地被考虑用于2型糖尿病(T2DM)的预防。本综述旨在总结迄今发表的关于在有T2DM风险的成年人中使用CGM和FGM的文献。

方法

对四个数据库(CINAHL、PsycINFO、MEDLINE、Cochrane图书馆)进行了系统检索,涵盖1985年至2024年的研究。符合条件的研究在针对有T2DM风险成年人的干预环境中使用了CGM或FGM。Rayyan软件协助进行文章筛选,约翰·霍普金斯循证实践工具评估研究质量。

结果

从13644篇文章中,纳入了12项研究,报告了来自八个国家的1144名参与者(353名有风险者,平均年龄47±12.8岁)。十项研究采用了FGM,重点关注与健康相关的行为(饮食、体育活动或两者兼有)。分别有75%和50%的研究报告了血糖控制和人体测量学方面的显著改善,同时糖化血红蛋白、空腹血糖和胰岛素抵抗也有所降低。七项研究使用了定性方法,反复出现的主题包括行为改变的感知益处和动机以及设备使用的可接受性和可行性。三项研究被评为“高”水平,证据质量得分为“B”,而其余研究在水平和证据质量方面均较低。

结论

现有发表的部署血糖监测技术的研究显示出有望支持旨在预防有风险成年人患T2DM的干预措施。需要进一步开展有力的研究来确认这些技术的长期可接受性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be65/11833802/9cb1ca9bb8b4/10.1177_19322968251315497-fig1.jpg

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