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将实时连续血糖监测仪作为低血糖指数和负荷饮食的一部分加以应用,并确定其对改善超重和肥胖青年成年人饮食摄入量、身体成分及代谢参数的影响:一项随机对照试验

Utilising a Real-Time Continuous Glucose Monitor as Part of a Low Glycaemic Index and Load Diet and Determining Its Effect on Improving Dietary Intake, Body Composition and Metabolic Parameters of Overweight and Obese Young Adults: A Randomised Controlled Trial.

作者信息

Chekima Khadidja, Noor Mohd Ismail, Ooi Yasmin Beng Houi, Yan See Wan, Jaweed Mohammad, Chekima Brahim

机构信息

Faculty of Health and Medical Sciences, Taylor's University, Selangor 47500, Malaysia.

Faculty of Medicine and Health Sciences, The National University of Malaysia, Selangor 43600, Malaysia.

出版信息

Foods. 2022 Jun 15;11(12):1754. doi: 10.3390/foods11121754.

Abstract

A randomised controlled trial to measure the effects of integrating real-time continuous glucose monitor (rtCGM) into a low glycaemic index (GI) and glycaemic load (GL) dietary intervention on dietary intake, body composition and specific metabolic parameters was carried out. A total of 40 overweight young adults [(means ± SD) age: 26.4 ± 5.3 years, BMI: 29.4 ± 4.7 kg/m2] were randomised into an intervention and control groups for a period of eight weeks. Both groups received nutrition education on low GI and GL foods. The intervention group also received an rtCGM system to monitor their glucose levels 24 h a day. While controlling for physical activities and GI and GL nutrition knowledge, the results indicated that the rtCGM system further improved body weight, BMI, fat mass, fasting plasma glucose, HbA1c, total cholesterol, HDL cholesterol and LDL cholesterol in the intervention group (p < 0.05). This trial unveils the robustness of the rtCGM where non-diabetic overweight and obese young adults can benefit from this device and utilise it as a management tool for overweight and obesity and a primary prevention tool for type 2 diabetes, as it provides real-time and personalised information on physiological changes.

摘要

开展了一项随机对照试验,以评估将实时连续血糖监测仪(rtCGM)纳入低血糖指数(GI)和血糖负荷(GL)饮食干预对饮食摄入量、身体成分和特定代谢参数的影响。共有40名超重的年轻成年人[(均值±标准差)年龄:26.4±5.3岁,BMI:29.4±4.7kg/m²]被随机分为干预组和对照组,为期8周。两组均接受了关于低GI和GL食物的营养教育。干预组还接受了一个rtCGM系统,用于每天24小时监测其血糖水平。在控制身体活动以及GI和GL营养知识的情况下,结果表明,rtCGM系统进一步改善了干预组的体重、BMI、脂肪量、空腹血糖、糖化血红蛋白、总胆固醇、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇(p<0.05)。该试验揭示了rtCGM的有效性,非糖尿病超重和肥胖的年轻成年人可以从该设备中受益,并将其用作超重和肥胖的管理工具以及2型糖尿病的一级预防工具,因为它提供了有关生理变化的实时和个性化信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de3e/9222336/f5e1825e54b2/foods-11-01754-g001.jpg

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