Sun Jiubo, Li Jing, Wang Xiaofei, Huo Xiaoguang, Xu Wenzhe, Li Fei
No. 2 Department of Oncology, Zibo Central Hospital, Zibo, China.
Department of Traditional Chinese Medicine, Zibo Central Hospital, Zibo, China.
Medicine (Baltimore). 2025 Feb 14;104(7):e41556. doi: 10.1097/MD.0000000000041556.
Primary cardiac angiosarcoma is very rare with a poor prognosis, and there is no recognized guideline for its diagnosis and treatment. Currently, there is no standardized adjuvant chemotherapy regimen following radical surgery for cardiac angiosarcoma. To date, the literature lacks reports on the use of albumin-bound paclitaxel as an adjuvant chemotherapy agent in this context. This case report aims to document and evaluate the imaging characteristics of the disease and the efficacy of albumin-bound paclitaxel as adjuvant chemotherapy, thereby providing valuable insights for clinical diagnosis and treatment.
We report a 70-year-old patient with right atrial angiosarcoma, who presented with atrial fibrillation as the initial symptom.
Transesophageal echocardiography, chest computed tomography, and cardiac magnetic resonance imaging showed a right atrial mass.
After radical resection, the patient was given 4 cycles of albumin-bound paclitaxel adjuvant chemotherapy.
Multiple metastases occurred in a short period of time, and the patient died 13 months after surgery. Surgical resection is the most important treatment for cardiac angiosarcoma, and the optimal adjuvant therapy needs to be further studied.
The limitation of this case report is its reliance on a single case, resulting in a limited sample size. To comprehensively characterize cardiac angiosarcoma and evaluate the efficacy of albumin-bound paclitaxel chemotherapy, future studies should collect additional cases and conduct long-term follow-up.
原发性心脏血管肉瘤非常罕见,预后较差,目前尚无公认的诊断和治疗指南。目前,心脏血管肉瘤根治性手术后尚无标准化的辅助化疗方案。迄今为止,文献中缺乏关于在此情况下使用白蛋白结合型紫杉醇作为辅助化疗药物的报道。本病例报告旨在记录和评估该疾病的影像学特征以及白蛋白结合型紫杉醇作为辅助化疗的疗效,从而为临床诊断和治疗提供有价值的见解。
我们报告了一名70岁的右心房血管肉瘤患者,最初症状为心房颤动。
经食管超声心动图、胸部计算机断层扫描和心脏磁共振成像显示右心房有肿块。
根治性切除术后,患者接受了4个周期的白蛋白结合型紫杉醇辅助化疗。
短期内出现多处转移,患者术后13个月死亡。手术切除是心脏血管肉瘤最重要的治疗方法,最佳辅助治疗方案有待进一步研究。
本病例报告的局限性在于仅依赖单个病例,样本量有限。为全面描述心脏血管肉瘤并评估白蛋白结合型紫杉醇化疗的疗效,未来研究应收集更多病例并进行长期随访。