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心脏手术后的对称性外周坏疽:一例病例报告及文献综述

Symmetrical peripheral gangrene after cardiac surgery: A case report and review of literature.

作者信息

Chen Xiaoliang, Shao Guofeng, Zhao Shunying, Li Ni

机构信息

Department of Cardiosurgery Intensive Care Unit, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.

Department of Cardiothoracic Surgery, Ningbo Medical Centre Lihuili Hospital, Ningbo University, Ningbo, China.

出版信息

Medicine (Baltimore). 2025 Feb 14;104(7):e41527. doi: 10.1097/MD.0000000000041527.

Abstract

RATIONALE

Cardiac surgery can cause arrhythmias and low cardiac output syndrome through various mechanisms, including cardiac manipulation, systemic inflammation, myocardial hypoxia, cardioplegic arrest, and ischemia resulting from coronary or graft occlusion. Symmetric peripheral gangrene is a rare but serious complication that can occur after cardiac surgery. Here, we present a case of symmetric peripheral gangrene shortly after cardiac surgery for mitral valve replacement.

PATIENT CONCERNS

A 76-year-old male with rheumatic heart disease and severe mitral stenosis underwent mitral valve replacement. He experienced postoperative bleeding on the first day after the cardiac surgery. After experiencing ventricular fibrillation, cardiogenic shock, acute hepatic failure, and disseminated intravascular coagulation (DIC), he developed symmetrical peripheral gangrene on the fifth day after cardiac surgery.

DIAGNOSES

The patient presented with postoperative bleeding, cardiogenic shock, and DIC complicated by symmetrical peripheral gangrene following cardiac surgery.

INTERVENTIONS

During cardiosurgery intensive care unit admission, the patient received positive inotropic agents and vasopressors, blood transfusion, and antithrombotic treatment with low -molecular-weight heparin. Because of the severe general condition of the patient, amputation was not performed.

OUTCOMES

The patient died on the 80th day after cardiac surgery because of multiorgan failure and DIC.

LESSONS

Physicians should be vigilant for comorbid symmetrical peripheral gangrene in patients undergoing cardiac surgery who present with postoperative bleeding, cardiogenic shock, and DIC. Early recognition of acrocyanosis, prompt management of cardiogenic shock, correction of anemia, hemodynamic stabilization, and properly controlled use of anticoagulation may help prevent symmetrical peripheral gangrene.

摘要

理论依据

心脏手术可通过多种机制导致心律失常和低心排血量综合征,包括心脏操作、全身炎症反应、心肌缺氧、心脏停搏以及冠状动脉或移植物闭塞导致的缺血。对称性外周坏疽是心脏手术后罕见但严重的并发症。在此,我们报告一例二尖瓣置换术后不久发生对称性外周坏疽的病例。

患者情况

一名76岁患有风湿性心脏病和严重二尖瓣狭窄的男性接受了二尖瓣置换术。心脏手术后第一天出现术后出血。经历室颤、心源性休克、急性肝衰竭和弥散性血管内凝血(DIC)后,在心脏手术后第五天出现对称性外周坏疽。

诊断

患者表现为心脏手术后术后出血、心源性休克和并发对称性外周坏疽的DIC。

干预措施

入住心脏外科重症监护病房期间,患者接受了正性肌力药物和血管升压药治疗、输血以及低分子量肝素抗栓治疗。由于患者全身状况严重,未进行截肢手术。

结果

患者在心脏手术后第80天因多器官功能衰竭和DIC死亡。

经验教训

对于心脏手术后出现术后出血、心源性休克和DIC的患者,医生应警惕合并对称性外周坏疽。早期识别肢端青紫、及时处理心源性休克、纠正贫血、稳定血流动力学以及合理控制抗凝治疗可能有助于预防对称性外周坏疽。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1053/11835120/31291febb768/medi-104-e41527-g001.jpg

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