婴儿暴发性细小病毒B19心肌炎——三例大流行后病例报告
Fulminant parvovirus B19 myocarditis in infants -report of three post-pandemic cases.
作者信息
Wahjudi Tatjana, Nitsch Alex, Sperhake Jan-Peter, Hoeger Peter H
机构信息
Department of Paediatrics, Catholic Children´s Hospital Wilhelmstift, Liliencronstr 130, 22149, Hamburg, Germany.
Dept. of Intensive Care/Paediatric Cardiology, Catholic Children´s Hospital Wilhelmstift, Liliencronstr 130, 22149, Hamburg, Germany.
出版信息
Eur J Clin Microbiol Infect Dis. 2025 May;44(5):1239-1243. doi: 10.1007/s10096-025-05072-1. Epub 2025 Feb 17.
Lack of immune stimulation ("immune debt") in the wake of the COVID-19 pandemic has led to a resurgence of many paediatric infectious diseases, recently including parvovirus B19 (PVB19). We observed three cases of fulminant PVB19 myocarditis in infants. All had experienced a short prodromal illness and succumbed to cardiogenic shock within 2-72 h after admission. The risk of fulminant myocarditis appears to be increased in infants. Further studies are needed to assess the incidence of fulminant myocarditis caused by PVB19, potentially linked to immune debt.
在新冠疫情之后，缺乏免疫刺激（“免疫债”）导致许多儿科传染病再度流行，最近包括细小病毒B19（PVB19）。我们观察到3例婴儿暴发性PVB19心肌炎病例。所有患儿都经历了短暂的前驱疾病，并在入院后2至72小时内因心源性休克死亡。婴儿发生暴发性心肌炎的风险似乎有所增加。需要进一步研究以评估由PVB19引起的、可能与免疫债有关的暴发性心肌炎的发病率。
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