Salem Razan, Hlavicka Jan, Hecker Florian, Seppelt Philipp C, Holubec Tomas, Leistner David M, Walther Thomas
Department of Cardiovascular Surgery, University Hospital and Goethe University Frankfurt, Frankfurt/Main, Germany.
Department of Cardiology, University Hospital and Goethe University Frankfurt, Frankfurt/Main, Germany.
JACC Case Rep. 2025 Feb 5;30(3):103119. doi: 10.1016/j.jaccas.2024.103119.
We present our surgical management of a mechanical transcatheter aortic valve replacement (TAVR) complication of an anterior mitral valve leaflet (AML) perforation with infective endocarditis.
Management consisted of surgical TAVR explantation, transaortic patch plasty of the AML perforation, patch plasty of an aortic laceration by the TAVR valve, and surgical aortic valve replacement.
In cases of high operative risk in a technically demanding surgical situation, the surgeon should aim to operate early and avoid extensive surgical trauma and long operation time by addressing the mitral valve through the aorta and choosing repair instead of replacement for AML perforation.
TAKE-HOME MESSAGES: Poor positioning of TAVR valves can result in severe structural and subsequent infectious complications. Early surgical treatment in high-risk older adult patients can be successfully performed, with favorable outcomes. Scrupulous asepsis and prophylactic perioperative antibiotic therapy are the most important prophylactic measures for prosthetic valve endocarditis.
我们展示了对一例经导管主动脉瓣置换术(TAVR)机械瓣导致前叶二尖瓣穿孔合并感染性心内膜炎的手术处理方法。
处理措施包括外科手术取出TAVR瓣膜、对二尖瓣前叶穿孔进行经主动脉补片修补、对TAVR瓣膜造成的主动脉撕裂进行补片修补以及外科主动脉瓣置换。
在技术要求高且手术风险大的情况下,外科医生应尽早手术,通过经主动脉处理二尖瓣,并选择修补而非置换二尖瓣前叶穿孔,以避免广泛的手术创伤和较长的手术时间。
TAVR瓣膜定位不佳可导致严重的结构及后续感染并发症。高危老年患者早期手术治疗可成功实施且预后良好。严格的无菌操作和围手术期预防性抗生素治疗是人工瓣膜心内膜炎最重要的预防措施。