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体位性震颤可能是进行性核上性麻痹的表现体征。

Orthostatic tremor as possible presenting sign of progressive supranuclear palsy.

作者信息

Maréchal Emke, Dekeyzer Sven, Crosiers David

机构信息

Department of Neurology, Antwerp University Hospital, Antwerp, Belgium.

Department of Neurology, Middelheim Hospital, Antwerp, Belgium.

出版信息

Clin Park Relat Disord. 2024 Oct 10;11:100275. doi: 10.1016/j.prdoa.2024.100275. eCollection 2024.

DOI:10.1016/j.prdoa.2024.100275
PMID:39963591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11832016/
Abstract

•Orthostatic tremor plus syndromes can be a presenting sign of movement disorders. We suggest remaining vigilant for other extrapyramidal symptoms during OT follow-up.•Orthostatic tremor is often difficult to treat but can sometimes respond to bilateral thalamic deep brain stimulation (DBS).•Diagnosis of PSP can be a challenge during the first years and MRI changes often only become apparent in later stages.

摘要

•直立性震颤加综合征可能是运动障碍的首发症状。我们建议在直立性震颤随访期间对其他锥体外系症状保持警惕。

•直立性震颤通常难以治疗，但有时对双侧丘脑深部脑刺激（DBS）有反应。

•进行性核上性麻痹（PSP）的诊断在最初几年可能具有挑战性，MRI改变通常在后期才会明显显现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1903/11832016/91a76aee6408/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1903/11832016/91a76aee6408/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1903/11832016/91a76aee6408/gr1.jpg

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1
Orthostatic tremor as possible presenting sign of progressive supranuclear palsy.体位性震颤可能是进行性核上性麻痹的表现体征。
Clin Park Relat Disord. 2024 Oct 10;11:100275. doi: 10.1016/j.prdoa.2024.100275. eCollection 2024.
2
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本文引用的文献

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Fast Orthostatic Tremor in Parkinson's Disease: Case Report and Comprehensive Review of Literature.帕金森病中的快速体位性震颤：病例报告及文献综述
Tremor Other Hyperkinet Mov (N Y). 2019 Sep 16;9. doi: 10.7916/tohm.v0.704. eCollection 2019.
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Comprehensive, blinded assessment of balance in orthostatic tremor.
对直立性震颤中的平衡进行全面、盲法评估。
Parkinsonism Relat Disord. 2018 Feb;47:22-25. doi: 10.1016/j.parkreldis.2017.11.335. Epub 2017 Nov 16.
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Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria.进行性核上性麻痹的临床诊断：运动障碍协会标准。
Mov Disord. 2017 Jun;32(6):853-864. doi: 10.1002/mds.26987. Epub 2017 May 3.
5
Associated movement disorders in orthostatic tremor.直立性震颤伴发的运动障碍。
J Neurol Neurosurg Psychiatry. 2012 Jul;83(7):725-9. doi: 10.1136/jnnp-2012-302436. Epub 2012 May 10.
6
Orthostatic tremor in progressive supranuclear palsy.进行性核上性麻痹中的直立性震颤。
Mov Disord. 2007 Jun 15;22(8):1192-4. doi: 10.1002/mds.21434.
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Natural history and syndromic associations of orthostatic tremor: a review of 41 patients.直立性震颤的自然病史及综合征关联：41例患者的综述
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Consensus statement of the Movement Disorder Society on Tremor. Ad Hoc Scientific Committee.运动障碍协会关于震颤的共识声明。特设科学委员会。
Mov Disord. 1998;13 Suppl 3:2-23. doi: 10.1002/mds.870131303.