Sandhu Harminder, Barr Derrick L, Tyre Lauri
Radiology, Michigan State University College of Osteopathic Medicine, Detroit, USA.
Diagnostic Radiology, Trinity Health, Pontiac, USA.
Cureus. 2025 Jan 18;17(1):e77633. doi: 10.7759/cureus.77633. eCollection 2025 Jan.
Acute aortic syndromes (AAS) include life-threatening conditions like penetrating atheromatous ulcer (PAU), which occurs when an atherosclerotic plaque erodes through the aortic wall. This can lead to complications such as intramural hematoma, pseudoaneurysm, or aortic rupture, especially in the ascending aorta. PAUs typically affect older males with atherosclerosis and are most commonly found in the lower descending thoracic aorta, with multiple PAUs being rare. This report highlights a case involving the incidental discovery of multiple PAUs and an associated ductus diverticulum, and it discusses their presentation and management. An 88-year-old male with a history of hypertension, diabetes, and pulmonary fibrosis presented with right-sided upper quadrant and chest pain radiating to the back. Initial imaging suggested progression of pulmonary fibrosis or an infection, but a subsequent CT angiogram revealed at least 12 focal outpouchings in the distal aortic arch and proximal descending thoracic aorta, compatible with PAUs. Additionally, a ductus diverticulum was identified. The patient was managed with high-dose statin therapy and scheduled for follow-up CTA in three months. This case highlights the incidental discovery of multiple PAUs and a ductus diverticulum, underscoring the rarity and complexity of PAU presentations. It emphasizes the importance of including PAU in the differential diagnosis for patients presenting with chest pain, especially when symptoms are atypical or overlap with other conditions. Early identification and management are crucial to prevent severe complications such as aortic dissection or rupture.
急性主动脉综合征(AAS)包括危及生命的疾病,如穿透性动脉粥样硬化溃疡(PAU),当动脉粥样硬化斑块侵蚀主动脉壁时就会发生这种情况。这可能导致诸如壁内血肿、假性动脉瘤或主动脉破裂等并发症,尤其是在升主动脉。PAU通常影响患有动脉粥样硬化的老年男性,最常见于降主动脉下段,多发PAU很少见。本报告重点介绍了一例偶然发现多发PAU及相关动脉导管憩室的病例,并讨论了其临床表现及处理方法。一名有高血压、糖尿病和肺纤维化病史的88岁男性,出现右上腹及胸痛并放射至背部。最初的影像学检查提示肺纤维化进展或感染,但随后的CT血管造影显示在主动脉弓远端和降主动脉近端至少有12个局灶性外凸,符合PAU表现。此外,还发现了一个动脉导管憩室。该患者接受了大剂量他汀类药物治疗,并计划在三个月后进行随访CTA检查。本病例突出了多发PAU和动脉导管憩室的偶然发现,强调了PAU表现的罕见性和复杂性。它强调了在胸痛患者的鉴别诊断中纳入PAU的重要性,尤其是当症状不典型或与其他疾病重叠时。早期识别和处理对于预防诸如主动脉夹层或破裂等严重并发症至关重要。