一种具有高促胰液素样生物活性的促胰液素前体。
A proform of secretin with high secretin-like bioactivity.
作者信息
Gafvelin G, Carlquist M, Mutt V
出版信息
FEBS Lett. 1985 May 20;184(2):347-52. doi: 10.1016/0014-5793(85)80636-0.
PMID:3996590
Abstract
A variant form of the heptacosapeptide amide secretin, with C-terminal -Val-Gly-Lys-Arg instead of valine amide, has been isolated from porcine upper intestinal tissue. Unexpectedly, this triacontapeptide exhibited a substantially higher bioactivity than the heptacosapeptide amide.
摘要
已从猪的上段肠道组织中分离出一种七肽酰胺促胰液素的变体形式，其C末端为-Val-Gly-Lys-Arg，而非缬氨酸酰胺。出乎意料的是，这种三十肽表现出比七肽酰胺显著更高的生物活性。
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