Ma Ying-Jie, Zhou Guang-Ming, Liu Zhi-Rong, Wei Jin-Fei, Li Xin-Yu, Dong Bin, Wu Lin-Juan, Wu Wen-Can, Yu Bo
National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
The Eye Hospital, School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou 325027, Zhejiang Province, China.
Int J Ophthalmol. 2025 Feb 18;18(2):244-250. doi: 10.18240/ijo.2025.02.07. eCollection 2025.
To investigate the clinical profile of patients with acquired lacrimal sac mucocele (ALSM) and evaluate the efficacy of endoscopic dacryocystorhinostomy (En-DCR) for this condition.
En-DCRs were performed on 141 patients with ALSM patients from January 2016 to March 2022. The clinical baseline information and magnetic resonance imaging (MRI) images were recorded and summarized. To assess the effectiveness of En-DCR therapy, both anatomical and functional success rate was assessed during a 12mo follow-up.
A total of 141 patients, with a mean age of 57.70±14.11y, were enrolled in this study. Majority of the patients were female (=91; 64.54%) and all had unilateral disease. All patients had a previous history of epiphora and purulent secretion, and the duration from lacrimal duct obstruction to mucocele formation ranged from 6 to 120mo. MRI findings consistently revealed an enlarged sac diameter, fluid accumulation separated by a thin rim from adjacent tissues, which is indicative of lacrimal sac mucocele. En-DCR was performed with an anatomical success rate of 93.62% and a functional success rate of 81.56%.
ALSM is more commonly seen in females and unilaterally. It is essentially a complication of lacrimal duct obstruction. MRI characteristics can be used for precise clinical diagnosis, while En-DCR emerges as an optimal therapy for this condition. Our results provide a comprehensive reference for the diagnosis and treatment of ALSM.
探讨获得性泪囊黏液囊肿（ALSM）患者的临床特征，并评估鼻内镜下泪囊鼻腔造口术（En-DCR）治疗该疾病的疗效。
对2016年1月至2022年3月期间的141例ALSM患者实施En-DCR手术。记录并总结患者的临床基线信息及磁共振成像（MRI）图像。为评估En-DCR治疗的有效性，在12个月的随访期内评估解剖学成功率和功能成功率。
本研究共纳入141例患者，平均年龄为57.70±14.11岁。大多数患者为女性（n = 91；64.54%），且均为单侧患病。所有患者既往均有溢泪和脓性分泌物病史，从泪道阻塞到黏液囊肿形成的病程为6至120个月。MRI检查结果一致显示囊腔直径增大，积液与相邻组织之间有一薄层分隔，提示泪囊黏液囊肿。实施En-DCR手术的解剖学成功率为93.62%，功能成功率为81.56%。
ALSM在女性中更为常见，且多为单侧发病。它本质上是泪道阻塞的一种并发症。MRI特征可用于精确的临床诊断，而En-DCR是治疗该疾病的最佳方法。我们的研究结果为ALSM的诊断和治疗提供了全面的参考。
