Chen Chao, Zhang Yihao, Gao Sineng, Wang Linfan, Zhang Ting, Li Tingting, Qian Xiaoqing, Chen Da
Department of Microelectronic Science and Engineering, School of Physical Science and Technology, Ningbo University, Ningbo, 315211, People's Republic of China.
Department of Chemical Engineering, Ningbo Polytechnic, Ningbo, 315800, People's Republic of China.
Mikrochim Acta. 2025 Feb 19;192(3):173. doi: 10.1007/s00604-025-07037-9.
Fluorine-doped carbon dots (F-CDs) are prepared through a one-pot hydrothermal method starting from ciprofloxacin, exhibiting a bright blue emission at 453 nm under the optical wavelength of 358 nm. The sensitive sensor for detecting Cu is established based on the fluorescence quenching of F-CDs, which is attributed to the static quenching caused by the formation of non-luminescent complexes between them. The limit of detection (LOD) is 46.2 nM. Meanwhile, a portable fluorescence sensor based on a lateral flow test strip (LFTS) has been developed for practical applications, which allows real-time monitoring of Cu with a satisfactory limit of detection (LOD) of 69.7 nM in a good linear range of 0.0697-50 μM. In addition, the identification of latent fingerprints (LFPs) based on F-CDs has been developed with the assistance of MATLAB, realizing high-performance fingerprint visualization and recognition. The results serve to underscore that the synthesized F-CDs not only provide a new tool for Cu detection in real samples, but also show great potential for LFPs visualization and information identification.
以环丙沙星为原料，通过一锅水热法制备了氟掺杂碳点（F-CDs），在358nm光波长下，F-CDs在453nm处呈现亮蓝色发射。基于F-CDs的荧光猝灭建立了检测铜的灵敏传感器，这归因于它们之间形成非发光络合物引起的静态猝灭。检测限（LOD）为46.2nM。同时，为实际应用开发了一种基于横向流动测试条（LFTS）的便携式荧光传感器，该传感器能够实时监测铜，在0.0697-50μM的良好线性范围内，检测限（LOD）为69.7nM，令人满意。此外，在MATLAB的辅助下，开发了基于F-CDs的潜在指纹（LFPs）识别方法，实现了高性能的指纹可视化和识别。结果强调，合成的F-CDs不仅为实际样品中的铜检测提供了一种新工具，而且在LFPs可视化和信息识别方面也显示出巨大潜力。
