基因特异性探针显示，在与该同种型睾酮非依赖性表达相关的H-2S等位基因中，C4-Slp基因存在选择性重复。 - Suppr

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超能文献

Gene-specific probes demonstrate selective duplications of the C4-Slp gene in the H-2S alleles associated with a testosterone-independent expression of this isotype.

作者信息

Lévi-Strauss M, Georgatsou E, Tosi M, Meo T

出版信息

Immunogenetics. 1985;21(4):397-401. doi: 10.1007/BF00430804.

DOI:10.1007/BF00430804

PMID:3997210

Abstract

摘要

相似文献

Gene-specific probes demonstrate selective duplications of the C4-Slp gene in the H-2S alleles associated with a testosterone-independent expression of this isotype.基因特异性探针显示，在与该同种型睾酮非依赖性表达相关的H-2S等位基因中，C4-Slp基因存在选择性重复。

Immunogenetics. 1985;21(4):397-401. doi: 10.1007/BF00430804.

Multiple duplications of complement C4 gene correlate with H-2-controlled testosterone-independent expression of its sex-limited isoform, C4-Slp.补体C4基因的多个重复与H-2控制的其性别限制同工型C4-Slp的非睾酮依赖性表达相关。

Proc Natl Acad Sci U S A. 1985 Mar;82(6):1746-50. doi: 10.1073/pnas.82.6.1746.

Duplications of complement and non-complement genes of the H-2S region: evolutionary aspects of the C4 isotypes and molecular analysis of their expression variants.H-2S区域补体和非补体基因的重复：C4同种型的进化方面及其表达变体的分子分析。

Immunol Rev. 1985 Oct;87:151-83. doi: 10.1111/j.1600-065x.1985.tb01149.x.

Regulation of expression of mouse C4 and Slp genes by non-H-2-linked genes.非H-2连锁基因对小鼠C4和Slp基因表达的调控。

Immunogenetics. 1989;29(1):6-13. doi: 10.1007/BF02341607.

Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).小鼠第四补体成分（C4）和性别限制蛋白（Slp）的结构与表达

Immunol Rev. 1985 Oct;87:101-22. doi: 10.1111/j.1600-065x.1985.tb01147.x.

Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.小鼠两个同源的MHC III类基因（C4和Slp）的重组，这解释了性限制蛋白表达对睾酮依赖性的丧失。

J Immunol. 1987 Jan 15;138(2):620-7.

The C4 and Slp genes of the complement region of the murine H-2 major histocompatibility complex.小鼠H-2主要组织相容性复合体补体区域的C4和Slp基因。

Philos Trans R Soc Lond B Biol Sci. 1984 Sep 6;306(1129):395-403. doi: 10.1098/rstb.1984.0100.

Mice constitutive for sex-limited protein (SLP) expression contain multiple Slp gene sequences.组成性表达性别限制蛋白（SLP）的小鼠含有多个Slp基因序列。

J Immunol. 1985 Jul;135(1):627-31.

Trans-regulatory genes affect Slpa and Slpo expression and act in a tissue-specific manner.反式调节基因影响Slpa和Slpo的表达，并以组织特异性方式发挥作用。

Immunogenetics. 1989;29(5):340-5. doi: 10.1007/BF00352844.

Male-specific expression of mouse sex-limited protein requires growth hormone, not testosterone.小鼠性别限制蛋白的雄性特异性表达需要生长激素，而非睾酮。

Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3626-30. doi: 10.1073/pnas.90.8.3626.

引用本文的文献

The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.雄激素依赖的C4-Slp基因由一个组成型活性启动子驱动。

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5786-90. doi: 10.1073/pnas.90.12.5786.

Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.鉴定负责小鼠补体C4和Slp基因转录调控差异的5'侧翼调控区。

Proc Natl Acad Sci U S A. 1986 Oct;83(20):7883-7. doi: 10.1073/pnas.83.20.7883.

Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.小鼠性限制蛋白雄激素依赖性和非依赖性表达的分子遗传学

Mol Cell Biol. 1987 May;7(5):1716-24. doi: 10.1128/mcb.7.5.1716-1724.1987.

Restriction fragment length polymorphism of C4 genes in mice with t chromosomes.

Immunogenetics. 1985;21(3):247-56. doi: 10.1007/BF00375377.

Extensive genomic polymorphism in mouse 21-hydroxylase region.小鼠21-羟化酶区域广泛的基因组多态性。

Immunogenetics. 1988;27(2):133-6. doi: 10.1007/BF00351087.

本文引用的文献

Female expression of the H-2-linked sex-limited protein (Slp) due to non-H-2 genes.由于非H-2基因导致的H-2连锁性限蛋白（Slp）的雌性表达。

Immunogenetics. 1980;10(1):19-29. doi: 10.1007/BF01561549.

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.通过与C4和性别限制蛋白（Slp）特异性cDNA杂交鉴定出的小鼠第四补体成分（C4）和性别限制蛋白（Slp）的基因。

Proc Natl Acad Sci U S A. 1984 Aug;81(15):4908-11. doi: 10.1073/pnas.81.15.4908.

H-2-linked murine factor B phenotypes.与H-2相关的小鼠B因子表型

Immunogenetics. 1983;17(1):67-78. doi: 10.1007/BF00364290.

The structural basis of the multiple forms of human complement component C4.人类补体成分C4多种形式的结构基础。

Cell. 1984 Apr;36(4):907-14. doi: 10.1016/0092-8674(84)90040-0.

Molecular map of the murine S region.小鼠S区域的分子图谱。

Proc Natl Acad Sci U S A. 1983 Nov;80(22):6947-51. doi: 10.1073/pnas.80.22.6947.

Molecular cloning and characterization of the gene coding for human complement protein factor B.编码人补体蛋白B因子的基因的分子克隆与特性分析

Proc Natl Acad Sci U S A. 1983 Jul;80(14):4464-8. doi: 10.1073/pnas.80.14.4464.

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).跨越小鼠第四补体成分（C4）前体中α-γ亚基连接处的cDNA克隆。

Proc Natl Acad Sci U S A. 1983 Aug;80(16):5061-5. doi: 10.1073/pnas.80.16.5061.

H-2 S region determined polymorphic variants of the C4, Slp, C2, and B complement proteins: a compilation.H-2 S区域决定的C4、Slp、C2和B补体蛋白的多态性变体：汇编

Immunogenetics. 1982;16(6):617-23. doi: 10.1007/BF00372032.

The C4 and Slp genes of the complement region of the murine H-2 major histocompatibility complex.小鼠H-2主要组织相容性复合体补体区域的C4和Slp基因。

Philos Trans R Soc Lond B Biol Sci. 1984 Sep 6;306(1129):395-403. doi: 10.1098/rstb.1984.0100.

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.与第四补体成分的C4和C4-Slp亚型相关的小鼠互补DNA克隆的序列异质性。

Philos Trans R Soc Lond B Biol Sci. 1984 Sep 6;306(1129):389-94. doi: 10.1098/rstb.1984.0099.

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