2型糖尿病中的糖尿病困扰及相关社会心理因素。一项基于人群的横断面研究。挪威的HUNT研究。

Diabetes distress and associated psychosocial factors in type 2 diabetes. A population-based cross-sectional study. The HUNT study, Norway.

作者信息

Riise Hilde K R, Haugstvedt Anne, Igland Jannicke, Graue Marit, Søfteland Eirik, Hermann Monica, Carlsson Sofia, Skinner Timothy C, Åsvold Bjørn Olav, Iversen Marjolein M

机构信息

Department of Health and Caring Sciences, Western Norway University of Applied Sciences, Bergen, Norway.

Haukeland University Hospital, Bergen, Norway.

出版信息

Diabetol Metab Syndr. 2025 Feb 19;17(1):62. doi: 10.1186/s13098-025-01631-w.

DOI:10.1186/s13098-025-01631-w

PMID:39972441

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11837721/

Abstract

BACKGROUND AND AIM

The world-wide prevalence of diabetes distress varies, and studies are mainly undertaken in clinical settings. By using data from the Trøndelag Health (HUNT) study, we aimed to estimate diabetes distress prevalence, its determinants, and associations with anxiety and depression among adults with type 2 diabetes.

METHODS

This population-based cross-sectional study consists of individuals ≥ 20 years with type 2 diabetes participating in the HUNT4 survey (2017-2019). Diabetes-distress prevalence with 95% confidence interval (CI) was calculated based on the five item Problem Areas in Diabetes (PAID-5) questionnaire. PAID-5 sum scores were rescaled to a 0-100 scale by multiplying the sum score by five. Linear and logistic regression models were used to examine associations of demographic, lifestyle- and clinical factors, with diabetes distress.

RESULTS

In total, 1954 individuals completed the PAID-5 questionnaire, with a mean score of 15.2 (SD 18.3) and 11.9% (95% CI 10.6-13.4) reporting high diabetes distress (PAID-5 ≥ 40). Multivariable linear regression showed that diabetes distress was associated with a 0.2 (95% CI 0.2-0.3) lower score for each year older age, 7.6 (95% CI 5.4-9.7) higher score for current insulin use, and 9.3 (95% CI 5.3-13.2) higher score for a history of diabetes foot ulcers. High levels of anxiety and depression symptoms were associated with higher diabetes distress (Anxiety: B 16.0, 95% CI 13.6-18.4, Depression: B 13.3, 95% CI 10.7-16.0).

CONCLUSIONS

Diabetes distress is common and strongly associated with younger age at diabetes onset, insulin use, foot ulcer, and anxiety and depression symptoms. Identifying and addressing diabetes distress in diabetes follow-up may facilitate improving health outcomes and prevent more serious mental health issues in individuals with T2D. Nevertheless, the findings should be further examined in longitudinal studies.

摘要

背景与目的

糖尿病困扰在全球的患病率各不相同，相关研究主要在临床环境中开展。通过使用特隆赫姆郡健康（HUNT）研究的数据，我们旨在估计2型糖尿病成年患者中糖尿病困扰的患病率、其决定因素以及与焦虑和抑郁的关联。

方法

这项基于人群的横断面研究纳入了参与HUNT4调查（2017 - 2019年）的年龄≥20岁的2型糖尿病患者。基于糖尿病问题领域五项问卷（PAID - 5）计算糖尿病困扰患病率及95%置信区间（CI）。PAID - 5总分通过将总分乘以5重新换算为0 - 100分制。使用线性和逻辑回归模型来检验人口统计学、生活方式和临床因素与糖尿病困扰的关联。

结果

共有1954人完成了PAID - 5问卷，平均得分为15.2（标准差18.3），11.9%（95%CI 10.6 - 13.4）报告有高度糖尿病困扰（PAID - 5≥40）。多变量线性回归显示，糖尿病困扰与年龄每增加一岁得分降低0.2（95%CI 0.2 - 0.3）、当前使用胰岛素得分升高7.6（95%CI 5.4 - 9.7）以及有糖尿病足溃疡病史得分升高9.3（95%CI 5.3 - 13.2）相关。高水平的焦虑和抑郁症状与更高的糖尿病困扰相关（焦虑：B 16.0，95%CI 13.6 - 18.4；抑郁：B 13.3，95%CI 10.7 - 16.0）。