Dewey Rebecca Susan, Dineen Robert A, Clemence Matthew, Menon Nitin, Bowtell Richard, Boyle Patrick, Hartley Douglas E H
Philips Healthcare, Best, Netherlands.
Nottingham University Hospitals NHS Trust, Queens Medical Centre, Nottingham, NG7 2UH, UK.
Otol Neurotol. 2025 Apr 1;46(4):e105-e108. doi: 10.1097/MAO.0000000000004445. Epub 2025 Feb 19.
To determine whether the internal auditory canal (IAC) can be visualized using magnetic resonance imaging (MRI) in users of a cochlear implant (CI) model that can safely undergo MRI at 3 T.
Four normally hearing controls and three individuals unilaterally implanted with a HiRes Ultra 3D (Advanced Bionics LLC, California, USA).
Participants underwent 3 T MRI using sequences appropriate for the postoperative surveillance of the IAC. Images in normally hearing individuals were acquired after placing a fully functional, unpowered, CI underneath a swimming cap at each of eight candidate scalp positions, four on each side of the head. Images were compared to a control condition without a CI present. and CI users were imaged with similar sequences.
In normally hearing controls, the likely impact of the artifact on detection of pathology for multiple neuroradiological locations as rated by two independent radiologists. In CI users, a qualitative assessment of the diagnostic usability of images.
Visibility of the ipsilateral IAC and cochlea varied among the three CI users, with images from one participant deemed largely usable, while those from the other two participants exhibited less diagnostic certainty, likely due to differences in implant locations and cranial/neuroanatomical variations. Ratings of images in normally hearing participants showed that more middle-to-anterior CI locations were associated with reduced likelihood of overlooking gross abnormalities.
Through meticulous surgical placement, bilateral IAC visualization may be achievable for monitoring chronic health conditions such as tumor surveillance in high-risk patients, and as a safety monitoring outcome measure in clinical trials.
确定在可安全接受3T磁共振成像（MRI）的人工耳蜗（CI）模型使用者中，能否通过MRI可视化内耳道（IAC）。
4名听力正常的对照者和3名单侧植入HiRes Ultra 3D（美国加利福尼亚州Advanced Bionics LLC公司）的个体。
参与者接受3T MRI检查，使用适合IAC术后监测的序列。在听力正常的个体中，将一个功能齐全、未通电的CI置于游泳帽下，分别置于头部两侧的8个候选头皮位置（每侧4个）后采集图像。将图像与不存在CI的对照情况进行比较。CI使用者也用类似序列进行成像。
在听力正常的对照者中，由两名独立放射科医生对伪影对多个神经放射学部位病变检测的可能影响进行评分。在CI使用者中，对图像的诊断可用性进行定性评估。
3名CI使用者中，同侧IAC和耳蜗的可视性各不相同，一名参与者的图像被认为基本可用，而另外两名参与者的图像诊断确定性较低，可能是由于植入位置和颅骨/神经解剖变异的差异。听力正常参与者的图像评分显示，CI位置越靠近中前部，忽略明显异常的可能性越低。
通过精心的手术放置，双侧IAC可视化对于监测高危患者的慢性健康状况（如肿瘤监测）以及作为临床试验中的安全监测结果指标可能是可行的。
