生物技术中的负责任人工智能：平衡发现、创新与生物安全风险
Responsible AI in biotechnology: balancing discovery, innovation and biosecurity risks.
作者信息
Wheeler Nicole E
机构信息
Department of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom.
出版信息
Front Bioeng Biotechnol. 2025 Feb 5;13:1537471. doi: 10.3389/fbioe.2025.1537471. eCollection 2025.
The integration of artificial intelligence (AI) in protein design presents unparalleled opportunities for innovation in bioengineering and biotechnology. However, it also raises significant biosecurity concerns. This review examines the changing landscape of bioweapon risks, the dual-use potential of AI-driven bioengineering tools, and the necessary safeguards to prevent misuse while fostering innovation. It highlights emerging policy frameworks, technical safeguards, and community responses aimed at mitigating risks and enabling responsible development and application of AI in protein design.
人工智能（AI）在蛋白质设计中的整合为生物工程和生物技术的创新带来了前所未有的机遇。然而，它也引发了重大的生物安全问题。本综述探讨了生物武器风险不断变化的形势、人工智能驱动的生物工程工具的两用潜力，以及在促进创新的同时防止滥用所需的保障措施。它强调了旨在降低风险并实现人工智能在蛋白质设计中的负责任开发和应用的新兴政策框架、技术保障措施和社区应对措施。
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