de Lima Renan Chaves, Quaresma Juarez Antonio Simões
Postgraduate Program in Tropical Diseases (PPGDT), Tropical Medicine Center, Federal University of Pará, Belém, PA, Brazil.
Responsible AI Committee, ABRIA-Brazilian Association of Artificial Intelligence, São Paulo, SP, Brazil.
Front Digit Health. 2025 Jun 4;7:1622123. doi: 10.3389/fdgth.2025.1622123. eCollection 2025.
The convergence of artificial intelligence and synthetic biology offers transformative opportunities to enhance global biosecurity. Emerging technologies promise rapid detection, containment, and mitigation of global biological threats, while simultaneously raising complex ethical and security challenges. This research aims to critically examine advances in AI applications for biosecurity, innovations in vaccine development enabled by synthetic biology, and the risks associated with the democratization of powerful biotechnological tools. We highlight both the potential and the dangers of integrating these technologies into public health preparedness systems and advocate for the establishment of robust governance frameworks to ensure their ethical and equitable implementation.
人工智能与合成生物学的融合为加强全球生物安全带来了变革性机遇。新兴技术有望快速检测、控制和缓解全球生物威胁，同时也带来了复杂的伦理和安全挑战。本研究旨在批判性地审视人工智能在生物安全应用方面的进展、合成生物学推动的疫苗开发创新，以及强大生物技术工具民主化所带来的风险。我们强调将这些技术整合到公共卫生防范系统中的潜力和危险，并主张建立强大的治理框架，以确保其符合伦理且公平地实施。
