Sdeeq Rashid Hoshanc, Bani-Saad Ali A, Ismail Mustafa
Department of Neurological Surgery, Erbil Teaching Hospital, Erbil, IRQ.
Department of Surgery, College of Medicine, University of Baghdad, Baghdad, IRQ.
Cureus. 2025 Jan 20;17(1):e77704. doi: 10.7759/cureus.77704. eCollection 2025 Jan.
Orbital abscesses, though rare, represent a serious complication of sinusitis and can result in significant morbidity, including permanent vision loss and intracranial spread if not managed promptly. This systematic review aims to provide a detailed analysis of the clinical presentation, diagnostic modalities, treatment approaches, and outcomes in patients with orbital abscesses. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive literature search was conducted across PubMed and Scopus, yielding 19 studies involving 36 patients with orbital abscesses. Data extraction focused on study design, sample size, patient demographics (age, gender), clinical presentation, diagnostic tools, treatment modalities, and outcomes, including resolution rates, complications, and recurrence. Orbital abscesses primarily affected younger populations, with a mean patient age of nine years. The most common symptoms solicited were proptosis at 75%, periorbital swelling at 80%, and pain at 70%. The diagnostic modality used in the majority, 89%, was imaging with computed tomography. All cases were given empiric intravenous antibiotics and third-generation cephalosporins, with added metronidazole. Of all the patients, 44% had to undergo any surgical intervention, usually in cases of larger abscesses or where the optic nerve was implicated. Endoscopic sinus surgery (ESS) was the most frequently used surgical approach, with a high success rate. A total of 78% of patients achieved complete resolution, and 80% experienced improved visual acuity. However, delayed intervention led to permanent vision loss in 5.5% of cases, highlighting the importance of timely treatment. The median hospital stay ranged from one to two weeks, depending on the severity of the condition and the treatment modality. Managing an orbital abscess requires early detection and treatment to avoid complications like loss of vision and intracranial extension. Smaller, medially located abscesses can be effectively treated with conservative antibiotic therapy, while larger or complicated cases require surgical treatment.
眼眶脓肿虽罕见,但却是鼻窦炎的严重并发症,若不及时处理,可导致严重的发病情况,包括永久性视力丧失和颅内扩散。本系统评价旨在对眼眶脓肿患者的临床表现、诊断方法、治疗方式及预后进行详细分析。本系统评价遵循系统评价和Meta分析的首选报告项目(PRISMA)指南。在PubMed和Scopus上进行了全面的文献检索,得到19项研究,涉及36例眼眶脓肿患者。数据提取集中在研究设计、样本量、患者人口统计学特征(年龄、性别)、临床表现、诊断工具、治疗方式及预后,包括治愈率、并发症和复发情况。眼眶脓肿主要影响年轻人群,患者平均年龄为9岁。最常见的症状是眼球突出(75%)、眶周肿胀(80%)和疼痛(70%)。大多数(89%)患者使用的诊断方法是计算机断层扫描成像。所有病例均给予经验性静脉抗生素治疗及第三代头孢菌素,并加用甲硝唑。所有患者中,44%必须接受手术干预,通常是在脓肿较大或累及视神经的情况下。内镜鼻窦手术(ESS)是最常用的手术方法,成功率较高。共有78%的患者实现了完全治愈,80%的患者视力得到改善。然而,延迟干预导致5.5%的病例出现永久性视力丧失,凸显了及时治疗的重要性。根据病情严重程度和治疗方式,中位住院时间为1至2周。处理眼眶脓肿需要早期发现和治疗,以避免视力丧失和颅内扩展等并发症。较小的、位于内侧的脓肿可通过保守抗生素治疗有效治愈,而较大或复杂的病例则需要手术治疗。