Ozan Fırat, Okur Kürşat Tuğrul, Özdemir Koray, Çavuş Mehmet, Karaman Hatice, Celik Ilhami
Orthopaedics and Traumatology, The University of Health Sciences, Kayseri City Training and Research Hospital, Kayseri, TUR.
Hand Surgery, The University of Health Sciences, Kayseri City Training and Research Hospital, Kayseri, TUR.
Cureus. 2025 Jan 20;17(1):e77735. doi: 10.7759/cureus.77735. eCollection 2025 Jan.
Background This study describes the long-term clinical and functional outcomes of patients with post-traumatic Cierny-Mader (C-M) Type III and IV chronic osteomyelitis (CO), managed by considering individual patient differences. Methods Twenty patients who developed CO of the long bones after trauma were included in this study. Data on the demographic characteristics of the patients, clinical and radiological characteristics, and surgical methods applied were collected. The classification system defined by C-M was used for CO classification. The Short Form-36 (SF-36) quality of life scale was used to evaluate the functional outcomes and quality of life of the patients at the end of follow-up. Results The participants included 16 males and four females, with an average age of 39.3 ± 14.5 years. The mean duration of CO was 6.8 ± 7.5 years. The anatomical location of the CO was in the tibia in 15 patients, in the femur in four, and in the radius in one. The mean follow-up time after CO reconstruction was 4.5 ± 1.05 years. According to the C-M anatomical classification, there were nine patients with Type III and 11 with Type IV. According to the C-M physiological classification, there was one patient with Class A, 16 with Class B1, and three with Class B2. Different combinations of surgical procedures were performed on each patient. The average number of surgical interventions performed on the patients was 3.1 ± 1.1. Culture growth was detected in 13 patients. At the end of follow-up, the patients' SF-36 scores were lower than those in the normal population. Conclusion Due to the varied histories of CO and individual differences, it is quite challenging to plan a standard treatment procedure for CO in clinical practice. Successful treatment can be achieved with a long-term multidisciplinary approach and individualized, well-planned treatment methods.
背景 本研究描述了创伤后Cierny-Mader(C-M)III型和IV型慢性骨髓炎(CO)患者的长期临床和功能结局,研究中考虑了个体患者差异。方法 本研究纳入了20例创伤后发生长骨CO的患者。收集了患者的人口统计学特征、临床和放射学特征以及所采用的手术方法的数据。采用C-M定义的分类系统对CO进行分类。使用简短健康调查简表36(SF-36)生活质量量表在随访结束时评估患者的功能结局和生活质量。结果 参与者包括16名男性和4名女性,平均年龄为39.3±14.5岁。CO的平均病程为6.8±7.5年。CO的解剖位置在胫骨的有15例,在股骨的有4例,在桡骨的有1例。CO重建后的平均随访时间为4.5±1.05年。根据C-M解剖学分类,III型有9例,IV型有11例。根据C-M生理学分类,A级有1例,B1级有16例,B2级有3例。对每位患者进行了不同的手术组合。患者接受手术干预的平均次数为3.1±1.1次。13例患者检测到培养物生长。随访结束时,患者的SF-36评分低于正常人群。结论 由于CO病史各异且存在个体差异,在临床实践中为CO制定标准治疗方案颇具挑战性。采用长期多学科方法以及个体化、精心规划的治疗方法可实现成功治疗。