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生物陶瓷与光固化三氧化矿物凝聚体作为间接盖髓剂的比较——一项随机对照试验。

Comparison between biodentine and light-cured mineral trioxide aggregate as an indirect pulp capping agent - A randomized controlled trial.

作者信息

Mangat Panna, Goswami Kartika, Solanki Mandeep, Rajput Neha

机构信息

Department of Conservative Dentistry and Endodontics, Kalka Dental College and Hospital, Meerut, Uttar Pradesh, India.

出版信息

J Conserv Dent Endod. 2025 Jan;28(1):78-83. doi: 10.4103/JCDE.JCDE_575_24. Epub 2025 Jan 13.

DOI:10.4103/JCDE.JCDE_575_24
PMID:39974684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11835355/
Abstract

BACKGROUND

Indirect pulp capping (IPC) represents a pivotal therapeutic intervention directed toward preservation of pulp vitality, achieved through the placement of a biocompatible, bioactive material over the affected dentin to protect the pulp from further insult and encourage healing.

AIM

This study aimed to evaluate the clinical and radiographical success rates of Biodentin versus light-cured mineral trioxide aggregate (MTA) when used as an IPC agents. Evaluation was done on the basis of prognosis of the treatment after a period of 1 year.

METHODOLOGY

This randomized controlled clinical trial was based on a cohort of 20 individuals with deep carious lesions being subsequently divided into two experimental groups of ten cases each. Group I - Biodentin and Group II - Light cured-MTA as pulp capping agents, respectively. Clinical and radiographical assessment was done at baseline, 1, 2, 3, 6 months, and 1 year.

RESULTS

Statistical analysis with the Chi-square test showed no statistically significant difference between the groups. The overall success rate of 1-year follow-up for both Biodentine group and Light-cured MTA group was 93.33%.

CONCLUSION

The results of this randomized controlled clinical trial support promising success of IPC independent of the pulp capping material used as the findings underscore a significant decrease in postoperative pain levels compared to preoperative states across all cases. However, more studies with long-term follow-ups are required.

摘要

背景

间接盖髓术(IPC)是一种关键的治疗干预措施,旨在通过在受影响的牙本质上放置生物相容性、生物活性材料来保护牙髓活力,防止牙髓受到进一步损伤并促进愈合。

目的

本研究旨在评估生物活性牙本质(Biodentin)与光固化三氧化矿物凝聚体(MTA)作为间接盖髓剂时的临床和影像学成功率。在1年的治疗期后,根据治疗预后进行评估。

方法

本随机对照临床试验以20例患有深龋病变的个体为队列,随后将其分为两个实验组,每组10例。第一组使用生物活性牙本质,第二组使用光固化MTA作为盖髓剂。在基线、1、2、3、6个月和1年时进行临床和影像学评估。

结果

卡方检验的统计分析表明两组之间无统计学显著差异。生物活性牙本质组和光固化MTA组1年随访的总体成功率均为93.33%。

结论

本随机对照临床试验的结果支持间接盖髓术具有良好的成功率,与所使用的盖髓材料无关,因为研究结果强调所有病例术后疼痛水平与术前状态相比显著降低。然而,需要更多的长期随访研究。

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本文引用的文献

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Immunohistochemical study of mixing mineral trioxide aggregate with hyaluronic acid as a pulp-capping agent in dog teeth.在犬齿中将矿物三氧化物凝聚体与透明质酸混合作为盖髓剂的免疫组织化学研究。
J Conserv Dent Endod. 2024 May;27(5):485-490. doi: 10.4103/JCDE.JCDE_88_24. Epub 2024 May 10.
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Push-out bond strength of mineral trioxide aggregate with addition of titanium dioxide, silver, and silicon dioxide nanoparticles: An comparative study.添加二氧化钛、银和二氧化硅纳米颗粒的三氧化矿物凝聚体的推出粘结强度:一项比较研究。
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Comparison of three different materials used for indirect pulp capping in permanent molars: An study.
用于恒牙间接盖髓的三种不同材料的比较:一项研究。
J Conserv Dent. 2022 Jan-Feb;25(1):68-71. doi: 10.4103/jcd.jcd_551_21. Epub 2022 May 2.
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Mineral Trioxide Aggregate Applications in Endodontics: A Review.矿物三氧化物凝聚体在牙髓病学中的应用:综述
Eur J Dent. 2020 Oct;14(4):683-691. doi: 10.1055/s-0040-1713073. Epub 2020 Jul 29.
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Comparative Microbiological Evaluation after Caries Removal by Various Burs.不同车针去除龋坏组织后的微生物学比较评估
Int J Clin Pediatr Dent. 2019 Nov-Dec;12(6):524-527. doi: 10.5005/jp-journals-10005-1678.
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Bio-Inductive Materials in Direct and Indirect Pulp Capping-A Review Article.直接和间接盖髓术中的生物诱导材料——一篇综述文章
Materials (Basel). 2020 Mar 7;13(5):1204. doi: 10.3390/ma13051204.
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Clinical and radiographic evaluation of indirect pulp capping with three different materials: a 2-year follow-up study.三种不同材料间接盖髓术的临床及影像学评价:一项为期 2 年的随访研究。
Eur J Paediatr Dent. 2019 Jun;20(2):105-110. doi: 10.23804/ejpd.2019.20.02.04.
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Clinical evaluation of biodentine: Its efficacy in the management of deep dental caries.生物活性玻璃陶瓷的临床评估:其在深龋治疗中的疗效
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